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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ATP6V0E1

ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1

ATP6V0E1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is possibly part of the V0 subunit. Since two nontranscribed pseudogenes have been found in dog, it is possible that the localization to chromosome 2 for this gene by radiation hybrid mapping is representing a pseudogene. Genomic mapping puts the chromosomal location on 5q35.3.

Gene Name: ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
Family/Subfamily: Transporter , ATPase - V type
Synonyms: ATP6V0E1, ATP6V0E, ATP6H, Vacuolar proton pump H subunit, V-ATPase subunit E 1, Atp6k, V-ATPase M9.2 subunit, Vma21p, M9.2, V-ATPase H subunit
Target Sequences: NM_003945 NP_003936.1 O15342

Filtered By: None
Type
Sandwich (1)
Target
ATP6V0E1 (1)
Reactivity
Mouse (1)
Sample Type
Cell Lysates (1)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
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Mouse ATP6V0E1 ELISA Kit (Sandwich ELISA) - LS-F52920
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate  $870.00
LSBio image for ELISA Kit
LSBio image for ELISA Kit
Showing 1-1 of 1 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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