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ATP6V0B
ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B
ATP6V0B is a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants.
| Gene Name: | ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B |
| Family/Subfamily: | Transporter , ATPase - V type |
| Synonyms: | ATP6V0B, ATP6F, HATPL, V-ATPase subunit c, VMA16 |
| Target Sequences: | NM_004047 NP_004038.1 Q99437 |
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