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ATG18 / WIPI1

WD repeat domain, phosphoinositide interacting 1

Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation-induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway.

Gene Name: WD repeat domain, phosphoinositide interacting 1
Synonyms: WIPI1, ATG18, Atg18 protein homolog, ATG18A, WIPI49, WIPI-1, WIPI 49 kDa, WIPI-1 alpha
Target Sequences: Q5MNZ9 Q5MNZ9

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Products
Antibodies (32)
Primary (32)
ATG18 / WIPI1 (32)
Human (32)
Mouse (16)
Rat (8)
Bat (8)
Bovine (4)
Chimpanzee (6)
Dog (4)
Gibbon (6)
Horse (8)
Pig (4)
Rabbit (8)
IHC (7)
IHC-P (3)
WB (32)
ELISA (13)
IF (1)
rabbit (25)
mouse (6)
rabbit-new zealand white (1)
Product Group
IHCPlus (2)
IgG (18)
IgG1 (6)
monoclonal mc (6)
polyclonal pc (26)
OTI10F4 (2)
OTI11B11 (2)
OTI8F9 (2)
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
Carrier-free (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (20)
aa202-232 (8)
aa195-446 (6)
aa35-84 (4)
aa359-408 (4)
aa187-446 (1)
aa32-59 (1)
aa350-400 (1)
No (32)
ATG18 / WIPI1 Antibody - Anti-ATG18 / WIPI1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$440
ATG18 / WIPI1 Antibody - Immunohistochemistry of paraffin-embedded human placenta using antibody at 1:100 dilution.
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa187-446) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$282; 100 µl/$348
ATG18 / WIPI1 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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ATG18 / WIPI1 Mouse anti-Human Monoclonal (aa195-446) (OTI11B11) Antibody
Human
IHC, WB
Unconjugated
100 µl/$409
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ATG18 / WIPI1 Mouse anti-Human Monoclonal (aa195-446) (Carrier-free) (OTI11B11) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$473
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$280; 120 µl/$343; 200 µl/$451
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ATG18 / WIPI1 Rabbit-New Zealand White anti-Human Polyclonal (aa350-400) Antibody
Human
IHC, WB
Unconjugated
100 µl/$369
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µl/$369; 200 µl/$411
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa202-232) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$642
Select
ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa202-232) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$825
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa202-232) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$825
Select
ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa202-232) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$825
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa202-232) (AP) Antibody
Human
ELISA, WB
AP Conjugated
200 µl/$825
Select
ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa202-232) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$825
Select
ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa202-232) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$825
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$347
ATG18 / WIPI1 Antibody - Western Blot (WB) analysis of HeLa SH-SY5Y 293T 3T3 cells using WIPI1 Polyclonal Antibody diluted at 1:800.
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$279; 100 µl/$309; 200 µl/$379
Select
ATG18 / WIPI1 Mouse anti-Human Monoclonal (aa195-446) (OTI8F9) Antibody
Human
WB
Unconjugated
100 µl/$409
Select
ATG18 / WIPI1 Mouse anti-Human Monoclonal (aa195-446) (Carrier-free) (OTI8F9) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$473
Select
ATG18 / WIPI1 Mouse anti-Human Monoclonal (aa195-446) (Carrier-free) (OTI10F4) Antibody
Mouse, Human
WB
Unconjugated, Carrier-free
100 µg/$473
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ATG18 / WIPI1 Mouse anti-Human Monoclonal (aa195-446) (OTI10F4) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$409
ATG18 / WIPI1 Antibody - WIPI1 Antibody western blot of human placenta tissue lysates (35 ug/lane). The WIPI1 antibody detected the WIPI1 protein (arrow).
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa32-59) Antibody
Human
WB
Unconjugated
400 µl/$376
ATG18 / WIPI1 Antibody - WIPI1 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa359-408) Antibody
Rabbit, Mouse, Dog, Horse, Bat, Human
WB
Unconjugated
100 µl/$414
ATG18 / WIPI1 Antibody - WIPI1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATG18 / WIPI1 Rabbit anti-Human Polyclonal (aa35-84) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Horse, Bat, Human
WB
Unconjugated
100 µl/$414
Viewing 1-25 of 32 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).