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Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity Probable.
Gene Name: | Activating Transcription Factor 7 Interacting Protein 2 |
Synonyms: | ATF7IP2, MCAF2, ATF7-interacting protein 2 |
Target Sequences: | NM_024997 NP_079273.2 Q5U623 |
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