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ATF1

activating transcription factor 1

ATF1 is an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.

Gene Name: activating transcription factor 1
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: ATF1, ATF-1, EWS-ATF1, FUS/ATF-1, Protein TREB36, TREB36
Target Sequences: NM_005171 NP_005162.1 P18846

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Products
Antibodies (99)
Primary (99)
ATF1 (99)
Human (91)
Mouse (45)
Rat (36)
Bovine (8)
Chimpanzee (9)
Dog (9)
Gibbon (9)
Guinea pig (9)
Hamster (6)
Horse (9)
Monkey (9)
Pig (8)
Rabbit (9)
Xenopus (3)
Zebrafish (6)
IHC (38)
IHC-P (21)
WB (94)
Flo (9)
ELISA (16)
ICC (2)
IF (8)
IP (5)
Peptide-ELISA (6)
RNAi (1)
rabbit (82)
mouse (15)
goat (2)
Product Group
IHCPlus (5)
IgG (47)
IgG1 (8)
IgG1,k (1)
IgG2a (2)
IgG2b (4)
monoclonal mc (15)
polyclonal pc (84)
3E7 (1)
OTI1D4 (2)
OTI2B4 (2)
OTI2C2 (2)
OTI5D10 (2)
OTI6B7 (2)
OTI7H3 (2)
OTI8G3 (2)
APC (3)
APC Conjugated (5)
Azide-free (1)
Biotin Conjugated (9)
Carrier-free (7)
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DY488 Conjugated (1)
DY550 Conjugated (1)
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HRP Conjugated (9)
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Preservative Free (1)
Unconjugated (54)
aa2-240 (8)
aa3-213 (8)
aa3-245 (8)
aa193-219 (7)
C-Terminus (5)
pSer63 (5)
N-Terminus (4)
aa179-228 (4)
aa70-119 (4)
1-80 aa (2)
150-230 aa, C-terminal (1)
N Terminus (1)
Thr209 (1)
aa1-210 (1)
aa1-271 (1)
aa1-50 (1)
aa171-221 (1)
aa176-225 (1)
aa221-271 (1)
aa31-80 (1)
p63 (1)
No (99)
ATF1 Antibody - Anti-ATF1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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ATF1 Mouse anti-Human Monoclonal (3E7) Antibody
Human
ELISA, IHC, IHC-P, RNAi, WB
Unconjugated
50 µg/$460
ATF1 Antibody - Immunohistochemical analysis of ATF1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ATF1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
ATF1 Antibody - Human, Skin: Formalin-Fixed Paraffin-Embedded (FFPE)
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ATF1 Rabbit anti-Human Polyclonal (aa176-225) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
ATF1 Antibody - Western blot of ATF-1 antibody
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ATF1 Rabbit anti-Human Polyclonal (150-230 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ATF1 Antibody - Western blot analysis of ATF1 (pS63) expression in HEK293T (A); NIH3T3 (B); mouse kidney (C) whole cell lysates.
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ATF1 Rabbit anti-Human Polyclonal (pSer63) Antibody
Mouse, Bovine, Human
IP, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
ATF1 Antibody
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ATF1 Rabbit anti-Mouse Polyclonal (aa3-245) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ATF1 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ATF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ATF1 Antibody - Anti-ATF1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATF1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ATF1 Antibody - Anti-ATF1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATF1 Rabbit anti-Human Polyclonal (aa179-228) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ATF1 Antibody - Anti-ATF1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATF1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ATF1 Antibody - Immunohistochemistry of paraffin-embedded human prostate using antibody at 1:100 dilution.
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ATF1 Rabbit anti-Human Polyclonal (aa1-210) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ATF1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-ATF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:150)
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ATF1 Mouse anti-Human Monoclonal (OTI2C2) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
ATF1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-ATF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:150)
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ATF1 Mouse anti-Human Monoclonal (OTI2B4) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
ATF1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-ATF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:150)
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ATF1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2B4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ATF1 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-ATF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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ATF1 Mouse anti-Human Monoclonal (OTI7H3) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
ATF1 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-ATF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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ATF1 Mouse anti-Human Monoclonal (Carrier-free) (OTI7H3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ATF1 Antibody - Western blot of ATF1 (T209) pAb in extracts from HepG2 cells.
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ATF1 Rabbit anti-Human Polyclonal (Thr209) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
ATF1 Antibody - IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-ATF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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ATF1 Mouse anti-Human Monoclonal (OTI8G3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
ATF1 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ATF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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ATF1 Mouse anti-Human Monoclonal (OTI5D10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
ATF1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ATF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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ATF1 Mouse anti-Human Monoclonal (Carrier-free) (OTI5D10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ATF1 Antibody - ATF1 antibody IHC-paraffin: Human Intestinal Cancer Tissue.
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ATF1 Rabbit anti-Human Polyclonal (aa1-271) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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ATF1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IHC-P
Unconjugated, Preservative Free
100 µl/$412
ATF1 Antibody - Staining HT29 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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ATF1 Rabbit anti-Human Polyclonal (pSer63) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ATF1 Antibody - Western blot of ATF-1 antibody
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ATF1 Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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ATF1 Rabbit anti-Human Polyclonal (aa193-219) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).