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ASF1A

anti-silencing function 1A histone chaperone

Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Gene Name: anti-silencing function 1A histone chaperone
Synonyms: ASF1A, Anti-silencing function 1A, CCG1-interacting factor A, CIA, HAsf1, Histone chaperone ASF1A, HSPC146, HCIA, CGI-98, DKFZP547E2110, HAsf1a
Target Sequences: NM_014034 NP_054753.1 Q9Y294

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).