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ASB14 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | ankyrin repeat and SOCS box containing 14 |
Synonyms: | ASB14, ASB-14 |
Target Sequences: | A6NK59 A6NK59 |
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