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ART1 /CD296

ADP-ribosyltransferase 1

ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2.

Gene Name: ADP-ribosyltransferase 1
Synonyms: ART1, ADP-ribosyltransferase 2, ART2, ARTC1, CD296, CD296 antigen, ADP-ribosyltransferase 1, Mono(ADP-ribosyl)transferase 1, RT6
Target Sequences: NM_004314 NP_004305.2 P52961

Publications (1)

1
Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity. Julia Hesse, Mona K Rosse, Bodo Steckel, Bernhard Blank-Landeshammer, Svenja Idel, Yvonne Reinders, Albert Sickmann, Norbert Sträter, Jürgen Schrader. Purinergic signalling. 2022 March;18:115-121. [Full Text Article] [PubMed:34961895] [PMC:PMC8850506]

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Proteins (7)
Native (1)
Over-Expression Lysate (2)
Recombinant (4)
ART1 /CD296 (7)
SDS-PAGE (1)
No (6)
Yes (1)
6His, N-terminus (1)
GST (1)
His, N-Terminal (1)
His,C-terminus (1)
Myc-DDK (Flag) (2)
Human (4)
Monkey-Cynomolgus (1)
293T Cells (1)
Chicken (1)
E. coli (2)
HEK 293 Cells (2)
Yeast (1)
Low endotoxin level (1)
ART1 /CD296 Protein
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant cynomolgus ART1 consists 283 amino acids and predicts a molecular mass of 31.7 kDa.
100 µg/$480
Select
E. coli
GST
57.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
ART1 /CD296 Protein
Select
Yeast
6His, N-terminus
32.5 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
ART1 /CD296 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.2 kDa
100 µg/$494
ART1 /CD296 Protein
Select
E. coli
His, N-Terminal
36.2 kDa
50 µg/$419
ART1 /CD296 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.2 kDa
20 µg/$150
ART1 /CD296 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Chicken
None
10 mg/$1,649; 1 mg/$361
Viewing 1-7 of 7 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).