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ARSB / Arylsulfatase B
arylsulfatase B
Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
| Gene Name: | arylsulfatase B |
| Synonyms: | ARSB, Arylsulfatase B, ASB, G4S, MPS6 |
| Target Sequences: | NM_000046 NP_000037.2 P15848 |
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