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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.
TCR Screening ServicesTest your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
E3 ubiquitin-protein ligase, which catalyzes polyubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3. May play a role in protein translation by mediating polyubiquitination of EIF4E2, leading to its subsequent degradation. Acts as the ligase involved in ISGylation of EIF4E2.
| Gene Name: | ariadne RBR E3 ubiquitin protein ligase 1 |
| Synonyms: | ARIH1, ARI, HARI, Monocyte protein 6, MOP-6, Protein ariadne-1 homolog, UbcH7-binding protein, ARI-1, UbcM4-interacting protein, H7-AP2, HHARI, MOP6, UBCH7BP |
| Target Sequences: | NM_005744 NP_005735.2 Q9Y4X5 |
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