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Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis.
Gene Name: | adenomatosis polyposis coli down-regulated 1 |
Synonyms: | APCDD1, B7323, FP7019, DRAPC1, HTS, Hypoptrichosis simplex, HHS, Protein APCDD1 |
Target Sequences: | Q3U128 Q3U128 |
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