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ANXA4 / Annexin IV

annexin A4

Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.

Gene Name: annexin A4
Synonyms: ANXA4, 35-beta calcimedin, ANX4, Annexin A4, Annexin IV, Annexin-4, Chromobindin-4, Endonexin I, Lipocortin IV, p32.5, PIG28, Proliferation-inducing gene 28, Protein II, ZAP36, p33/41, PAP-II, PP4-X
Target Sequences: NM_001153 NP_001144.1 P09525

Publications (1)

1
CD6 Receptor Regulates Intestinal Ischemia/Reperfusion-induced Injury by Modulating Natural IgM-producing B1a Cell Self-renewal. Enyindah-Asonye G, Li Y, Xin W, Singer NG, Gupta N, Fung J, Lin F. The Journal of biological chemistry. 2017 January;292:661-671. [Full Text Article] [PubMed:27909060] [PMC:PMC5241740]

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Proteins (20)
Over-Expression Lysate (2)
Recombinant (18)
ANXA4 / Annexin IV (20)
No (19)
Yes (1)
10His, N-terminus + Myc, C-terminus (1)
10His-SUMO, N-terminus + Myc, C-terminus (2)
GST (1)
GST, N-terminus (1)
His (10)
His-T7 (1)
Myc-DDK (Flag) (3)
Bovine (1)
Dog (3)
Human (8)
Mouse (3)
Pig (2)
Rat (2)
293T Cells (1)
E. coli (15)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (5)
ANXA4 / Annexin IV Protein - Recombinant Annexin A4 By SDS-PAGE
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E. coli
His
20.1 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
ANXA4 / Annexin IV Protein
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E. coli
None
100 µg/$511; 500 µg/$1,348; 20 µg/$311
ANXA4 / Annexin IV Protein - Recombinant Annexin A4 By SDS-PAGE
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E. coli
His
18.7 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
ANXA4 / Annexin IV Protein - Recombinant Annexin A4 By SDS-PAGE
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E. coli
His
15.5 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
ANXA4 / Annexin IV Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-SUMO, N-terminus + Myc, C-terminus
55.8 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
ANXA4 / Annexin IV Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
40.8 kDa
20 µg/$405; 1 mg/$1,679; 100 µg/$598
ANXA4 / Annexin IV Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.9 kDa
100 µg/$494
ANXA4 / Annexin IV Protein - Recombinant  Annexin A4 By SDS-PAGE
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E. coli
His-T7
21.9 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
ANXA4 / Annexin IV Protein - 12.5% SDS-PAGE of human ANXA4 stained with Coomassie Blue
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Wheat Germ Extract
GST
61.05 kDa
10 µg/$479; 25 µg/$670
ANXA4 / Annexin IV Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
35.9 kDa
20 µg/$150
ANXA4 / Annexin IV Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His-SUMO, N-terminus + Myc, C-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
ANXA4 / Annexin IV Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ANXA4 / Annexin IV Protein - Purified recombinant protein ANXA4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
35.9 kDa
20 µg/$1,107
ANXA4 / Annexin IV Protein - Recombinant Annexin A4 By SDS-PAGE
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E. coli
His
20.3 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
ANXA4 / Annexin IV Protein - Recombinant Annexin A4 By SDS-PAGE
Select
E. coli
His
18.5 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
ANXA4 / Annexin IV Protein - Recombinant Annexin A4 By SDS-PAGE
Select
E. coli
His
12.7 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Select
E. coli
His
20.4 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
Select
E. coli
His
18.1 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
Select
E. coli
His
15.3 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Select
E. coli
His
19.1 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).