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ANGPT2 / Angiopoietin-2

angiopoietin 2

Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Gene Name: angiopoietin 2
Synonyms: ANGPT2, AGPT2, Angiopoietin-2, Angiopoietin-2a, Angiopoietin-2B, ANG-2, Angiopoietin 2, ANG2, Tie2-ligand
Target Sequences: NM_001147 NP_001138.1 O15123

Publications (1)

1
Angiopoietin/Tie2 Signaling Transforms Capillaries into Venules Primed for Leukocyte Trafficking in Airway Inflammation. Jonas Fuxe, Erin Lashnits, Shaun O'Brien, Peter Baluk, Sebastien P. Tabruyn, Frank Kuhnert, Calvin Kuo, Gavin Thurston and Donald M. McDonald. The American journal of pathology. 2010 176:2009-18. (ICC, IHC, WB; Mouse, Human) [Full Text Article] [PubMed:20133818] [PMC:PMC2843488]

☰ Filters
Proteins (3)
Antibodies (1)
ELISA Kits (1)
Primary (1)
Recombinant (3)
Sandwich CLIA (1)
ANGPT2 / Angiopoietin-2 (5)
Mouse (1)
Rat (1)
Rabbit (1)
IHC (1)
rabbit (1)
IgG (1)
polyclonal pc (1)
Unconjugated (1)
No (5)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
6His, C-terminus (1)
Fc, C-terminus (2)
Human (1)
Mouse (1)
Rhesus monkey (1)
Human (3)
Low endotoxin level (3)
ANGPT2 / Angiopoietin-2 Antibody - Immunohistochemistry of paraffin-embedded Mouse kidney using ANGPT2 Polycloanl Antibody at dilution of 1:200.
Select
ANGPT2 / Angiopoietin-2 Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat
IHC
Unconjugated
20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439
ANGPT2 / Angiopoietin-2 Protein - Recombinant Mouse Angiopoietin-2/ANG2 (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
81.4 kDa
10 µg/$294; 50 µg/$460
ANGPT2 / Angiopoietin-2 Protein - Recombinant Rhesus Macaque Angiopoietin-2/ANG2 (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
81.7 kDa
10 µg/$338; 50 µg/$628
ANGPT2 / Angiopoietin-2 Protein - Recombinant Human Angiopoietin-2/ANG2 (C-6His)
Select
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.6 kDa
10 µg/$294; 50 µg/$460
ANGPT2 / Angiopoietin-2 ELISA Kit
Select
Sandwich CLIA
Rabbit
0.156 - 10 ng/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$697
Viewing 1-5 of 5 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).