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ANAPC11 / APC11
anaphase promoting complex subunit 11
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
| Gene Name: | anaphase promoting complex subunit 11 |
| Synonyms: | ANAPC11, Apc11p, APC11, Cyclosome subunit 11, HSPC214 |
| Target Sequences: | NM_016476 NP_057560.8 Q9NYG5 |
Publications (2)
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