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ALOX5AP / FLAP

arachidonate 5-lipoxygenase-activating protein

ALOX5AP / FLAP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene Name: arachidonate 5-lipoxygenase-activating protein
Synonyms: ALOX5AP, FLAP, MK-886-binding protein
Target Sequences: NM_001629 NP_001620.2 P20292

☰ Filters
Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
ALOX5AP / FLAP (6)
No (6)
6His-SUMO, N-terminus (1)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
Baculovirus (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (1)
ALOX5AP / FLAP Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
34.2 kDa
100 µg/$1,801; 20 µg/$1,247
ALOX5AP / FLAP Protein - Purified recombinant protein ALOX5AP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
18 kDa
20 µg/$1,107
ALOX5AP / FLAP Protein - 12.5% SDS-PAGE of human ALOX5AP stained with Coomassie Blue
Select
Wheat Germ Extract
GST
43.45 kDa
10 µg/$479; 25 µg/$670
ALOX5AP / FLAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18 kDa
20 µg/$150
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
19 kDa
100 µg/$1,047
ALOX5AP / FLAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).