ALOX5 / 5-LOX

arachidonate 5-lipoxygenase

ALOX5 / 5-LOX is a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Antibodies (98)

ELISA Kits (25)

Proteins (8)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Competitive EIA (4)

Custom (1)

Over-Expression Lysate (2)

Primary (98)

Recombinant (6)

Sandwich (15)

Sandwich CLIA (3)

Target

ALOX5 / 5-LOX (131)

Reactivity

Human (90)

Mouse (58)

Rat (36)

Bovine (9)

Chimpanzee (3)

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Gibbon (3)

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IHC (36)

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Host

rabbit (74)

mouse (23)

goat (1)

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IHCPlus (4)

Isotype

IgG (36)

IgG1 (12)

IgG2a (4)

Clonality

monoclonal mc (23)

polyclonal pc (75)

Clone

OTI1A1 (2)

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OTI1D6 (2)

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aa18-364 (16)

aa461-671 (15)

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Glu267 (1)

Ser272 (1)

aa120-483 (1)

aa130-149 (1)

aa246-295 (1)

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Publications

No (130)

Yes (1)

Sample Type

Adherent Cell Cultures (2)

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Cell Lysates (4)

Plasma (15)

Serum (15)

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Tag

GST (1)

His (2)

His, N-Terminal (2)

Myc-DDK (Flag) (3)

Species

Human (4)

Mouse (2)

Rat (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ ALOX5 / 5-LOX Antibody (aa130-149) LS-B1499

(4.0) Rating

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal (aa130-149) Antibody

Reactivity:

Bovine, Rat, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

1 Each/$485

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IHC-plus™ ALOX5 / 5-LOX Antibody (aa600-674) LS-B2164

(4.0) Rating

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal (aa600-674) Antibody

Reactivity:

Rabbit, Mouse, Bovine, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$460

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Human ALOX5 / 5-LOX (Sandwich ELISA) ELISA Kit - LS-F4570

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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IHC-plus™ ALOX5 / 5-LOX Antibody (aa100-200) LS-B2144

(4.0) Rating

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal (aa100-200) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$460

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Mouse ALOX5 / 5-LOX (Sandwich ELISA) ELISA Kit - LS-F11968

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human ALOX5 / 5-LOX (Sandwich ELISA) ELISA Kit - LS-F20873

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat ALOX5 / 5-LOX (Sandwich ELISA) ELISA Kit - LS-F5780

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$856

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ALOX5 / 5-LOX Antibody (phospho-Ser271) LS-C198639

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal (pSer271) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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IHC-plus™ ALOX5 / 5-LOX Antibody (aa246-295) LS-B8370

(4.0) Rating

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal (aa246-295) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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ALOX5 / 5-LOX Antibody (C-Terminus) LS-C201775

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ALOX5 / 5-LOX Antibody LS-C806387

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Mouse ALOX5 / 5-LOX (CLIA) ELISA Kit - LS-F31032

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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ALOX5 / 5-LOX Antibody (aa120-483) LS-C357441

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal (aa120-483) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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Human ALOX5 / 5-LOX Protein (Recombinant His, N-Terminal) (aa461-671) - LS-G13698

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

25.9 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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ALOX5 / 5-LOX Antibody (aa18-364, clone OTI1A1) LS-C798978

Antibody:

ALOX5 / 5-LOX Mouse anti-Human Monoclonal (aa18-364) (OTI1A1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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ALOX5 / 5-LOX Antibody (aa18-364, clone OTI1A1, Carrier-free) LS-C791054

Antibody:

ALOX5 / 5-LOX Mouse anti-Human Monoclonal (aa18-364) (Carrier-free) (OTI1A1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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ALOX5 / 5-LOX Antibody (aa18-364, clone OTI1C1) LS-C793975

Antibody:

ALOX5 / 5-LOX Mouse anti-Human Monoclonal (aa18-364) (OTI1C1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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ALOX5 / 5-LOX Antibody (aa18-364, clone OTI1C1, Carrier-free) LS-C791055

Antibody:

ALOX5 / 5-LOX Mouse anti-Human Monoclonal (aa18-364) (Carrier-free) (OTI1C1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX5 / 5-LOX Antibody (aa18-364, clone OTI2C5) LS-C793983

Antibody:

ALOX5 / 5-LOX Mouse anti-Human Monoclonal (aa18-364) (OTI2C5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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ALOX5 / 5-LOX Antibody (aa18-364, clone OTI2C5, Carrier-free) LS-C791090

Antibody:

ALOX5 / 5-LOX Mouse anti-Human Monoclonal (aa18-364) (Carrier-free) (OTI2C5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX5 / 5-LOX Antibody (aa18-364, clone OTI3F1) LS-C793985

Antibody:

ALOX5 / 5-LOX Mouse anti-Human Monoclonal (aa18-364) (OTI3F1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

ALOX5 / 5-LOX Antibody (aa18-364, clone OTI3F1, Carrier-free) LS-C791091

Antibody:

ALOX5 / 5-LOX Mouse anti-Human Monoclonal (aa18-364) (Carrier-free) (OTI3F1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX5 / 5-LOX Antibody LS-C659378

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$341

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ALOX5 / 5-LOX Antibody (220-300 aa) LS-C381310

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal (220-300 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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ALOX5 / 5-LOX Antibody (220-300 aa) LS-C381825

Antibody:

ALOX5 / 5-LOX Rabbit anti-Human Polyclonal (220-300 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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