ALOX15B / 15-LOX-2

arachidonate 15-lipoxygenase, type B

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.

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Products

Proteins (10)

Type

Over-Expression Lysate (6)

Recombinant (4)

Target

ALOX15B / 15-LOX-2 (10)

Publications

No (10)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (6)

Species

Human (6)

Rat (1)

Source

293T Cells (3)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human ALOX15B / 15-LOX-2 Protein (Recombinant GST, N-terminus) (aa181-280) - LS-G57754

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Rat ALOX15B / 15-LOX-2 Protein (Recombinant His-T7) (aa349-633) - LS-G24288

Source:

E. coli

Tag:

His-T7

Molecular Weight:

35.8 kDa

Price:

10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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ALOX15B / 15-LOX-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99342

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75.7 kDa

Price:

100 µg/$710

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Human ALOX15B / 15-LOX-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81816

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

72.3 kDa

Price:

20 µg/$215

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Human ALOX15B / 15-LOX-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81817

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.2 kDa

Price:

20 µg/$215

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Human ALOX15B / 15-LOX-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81819

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75.7 kDa

Price:

20 µg/$215

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ALOX15B / 15-LOX-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120571

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

72.3 kDa

Price:

100 µg/$710

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ALOX15B / 15-LOX-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120572

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.2 kDa

Price:

100 µg/$710

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Human ALOX15B / 15-LOX-2 Protein (Recombinant GST) (Full Length) - LS-G27432

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

102.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ALOX15B / 15-LOX-2 Protein (Recombinant His-T7) (aa253-490) - LS-G13690

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.5 kDa

Price:

50 µg/$430; 10 µg/$279; 200 µg/$857; 100 µg/$687; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142

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