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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ALOX15 / 15-Lipoxygenase

arachidonate 15-lipoxygenase

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.

Gene Name: arachidonate 15-lipoxygenase
Synonyms: ALOX15, 15-lipoxygenase, 15-LOX, 15-lipooxygenase-1, 15-LO-1, 15LOX-1, 15-LOX-1, LOG15, Arachidonate 15-lipoxygenase
Target Sequences: NM_001140 NP_001131.3 P16050

Filtered by: None
Target
ALOX15 / 15-Lipoxygenase (54)
Reactivity
Human (54)
Mouse (18)
Rat (12)
Chimpanzee (3)
Dog (2)
Gibbon (3)
Monkey (8)
Orangutan (3)
Pig (4)
Rabbit (5)
Application
IHC (25)
IHC-P (9)
WB (53)
Flo (4)
ELISA (11)
ICC (1)
IF (6)
Peptide-ELISA (1)
Host
rabbit (29)
mouse (23)
goat (1)
sheep (1)
Isotype
IgG (21)
IgG2a (2)
IgG2a,k (7)
IgG2b (6)
Clonality
monoclonal mc (23)
polyclonal pc (31)
Clone
3D8 (1)
7H6 (2)
OTI2G3 (2)
OTI3G8 (2)
OTI8C5 (2)
Format
AP Conjugated (2)
APC (2)
APC Conjugated (4)
Biotin Conjugated (5)
Carrier-free (4)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (25)
Epitope
aa170-312 (16)
aa539-588 (4)
aa2-337 (1)
aa482-494 (1)
aa610-643 (1)
Publications
No (54)
Showing 1-25 of 54 results

IHC-plus™ ALOX15 / 15-Lipoxygenase Antibody (clone 3D8) LS-B4278
Mouse Monoclonal [clone 3D8] (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg  $495.00
Anti-ALOX15 / 15 Lipoxygenase 1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
ALOX15 monoclonal antibody, clone 3D8 Western blot of ALOX15 expression in HeLa NE.

ALOX15 / 15-Lipoxygenase Antibody (clone OTI2G3) LS-C173699
Mouse Monoclonal [clone OTI2G3] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Human
Flo, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-ALOX15 mouse monoclonal antibody.
IHC of paraffin-embedded Human Kidney tissue using anti-ALOX15 mouse monoclonal antibody.

ALOX15 / 15-Lipoxygenase Antibody (clone OTI2G3, Carrier-free) LS-C786815
Mouse Monoclonal [clone OTI2G3] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-ALOX15 mouse monoclonal antibody.
IHC of paraffin-embedded Human Kidney tissue using anti-ALOX15 mouse monoclonal antibody.

IHC-plus™ ALOX15 / 15-Lipoxygenase Antibody (clone 7H6) LS-B12236
Mouse Monoclonal [clone 7H6] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)

ALOX15 / 15-Lipoxygenase Antibody (aa539-588) LS-C111783
Rabbit Polyclonal to Human ALOX15 / 15-Lipoxygenase
Rabbit, Mouse, Rat, Pig, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $385.00
ALOX15 / 15 Lipoxygenase 1 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALOX15 / 15-Lipoxygenase Antibody (aa2-337) LS-C343940
Rabbit Polyclonal to Human ALOX15 / 15-Lipoxygenase
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg 200µl 0.5mg/ml  $355.00
ALOX15 antibody IHC-paraffin: Mouse Lung Tissue.
ALOX15 antibody IHC-paraffin: Rat Lung Tissue.

IHC-plus™ ALOX15 / 15-Lipoxygenase Antibody (aa482-494) LS-B6689
Goat Polyclonal to Human ALOX15 / 15-Lipoxygenase
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-ALOX15 / 15 Lipoxygenase 1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.
Anti-ALOX15 / 15 Lipoxygenase 1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.

ALOX15 / 15-Lipoxygenase Antibody LS-C402970
Rabbit Polyclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human thyroid cancer using ALOX15 Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of paraffin-embedded Human breast cancer using ALOX15 Polyclonal Antibody at dilution of 1:60.

IHC-plus™ ALOX15 / 15-Lipoxygenase Antibody LS-B7902
Sheep Polyclonal to Rabbit ALOX15 / 15-Lipoxygenase
Rabbit, Mouse, Human
IHC, IHC-P, WB
Unconjugated
1ea  $425.00
Anti-15-LOX / ALOX15 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Western blot of 15-LOX / ALOX15 antibody.

ALOX15 / 15-Lipoxygenase Antibody (clone 7H6, Carrier-free) LS-C786937
Mouse Monoclonal [clone 7H6] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)

ALOX15 / 15-Lipoxygenase Antibody (clone OTI3G8) LS-C173722
Mouse Monoclonal [clone OTI3G8] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human breast tissue using anti-ALOX15 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-ALOX15 mouse monoclonal antibody.

ALOX15 / 15-Lipoxygenase Antibody (clone OTI3G8, Carrier-free) LS-C786848
Mouse Monoclonal [clone OTI3G8] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Dog, Rat, Human, Monkey
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
IHC of paraffin-embedded Human breast tissue using anti-ALOX15 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-ALOX15 mouse monoclonal antibody.

ALOX15 / 15-Lipoxygenase Antibody (aa610-643) LS-C99452
Rabbit Polyclonal to Human ALOX15 / 15-Lipoxygenase
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
200µl  $325.00
Formalin-fixed and paraffin-embedded human lymph tissue reacted with ALOX15 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Confocal immunofluorescence of ALOX15 Antibody with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

ALOX15 / 15-Lipoxygenase Antibody (aa170-312, FITC) LS-C304832
Mouse Monoclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Human
WB
FITC Conjugated
100µl 0.5mg/ml  $275.00; 200µl 0.5mg/ml  $365.00; 1ml 0.5mg/ml  $605.00
Western blot of recombinant 15-LOX / ALOX15.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ALOX15 / 15-Lipoxygenase Antibody LS-C659218
Rabbit Polyclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IF, IHC, WB
Unconjugated
100µg  $405.00

ALOX15 / 15-Lipoxygenase Antibody (HRP) LS-C543422
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
HRP Conjugated
100µl  $710.00

ALOX15 / 15-Lipoxygenase Antibody (Biotin) LS-C523294
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
Biotin Conjugated
100µl  $710.00

ALOX15 / 15-Lipoxygenase Antibody (FITC) LS-C533334
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
FITC Conjugated
100µl  $710.00

ALOX15 / 15-Lipoxygenase Antibody (APC) LS-C515037
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
APC Conjugated
100µl  $710.00

ALOX15 / 15-Lipoxygenase Antibody (PE) LS-C651532
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
PE Conjugated
100µl  $710.00

ALOX15 / 15-Lipoxygenase Antibody (AP) LS-C505364
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
AP Conjugated
100µl  $710.00

ALOX15 / 15-Lipoxygenase Antibody LS-C349291
Rabbit Polyclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Mouse, Rat, Human
IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded rat lung tissue.
Immunohistochemistry of paraffin-embedded human stomach cancer tissue.

ALOX15 / 15-Lipoxygenase Antibody (clone OTI8C5, Carrier-free) LS-C786846
Mouse Monoclonal [clone OTI8C5] (IgG2a) to Human ALOX15 / 15-Lipoxygenase
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALOX15 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALOX15.

ALOX15 / 15-Lipoxygenase Antibody LS-C667705
Rabbit Polyclonal to Human ALOX15 / 15-Lipoxygenase
Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunohistochemistry - Paraffin Image
Western blot Image

ALOX15 / 15-Lipoxygenase Antibody LS-C764003
Rabbit Polyclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Mouse, Rat, Human, Monkey
IHC, WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00
Showing 1-25 of 54 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).