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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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ALOX15 / 15-Lipoxygenase

arachidonate 15-lipoxygenase

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.

Gene Name: arachidonate 15-lipoxygenase
Synonyms: ALOX15, 15-lipoxygenase, 15-LOX, 15-lipooxygenase-1, 15-LO-1, 15LOX-1, 15-LOX-1, LOG15, Arachidonate 15-lipoxygenase
Target Sequences: NM_001140 NP_001131.3 P16050


ALOX15 / 15-Lipoxygenase Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Mouse Monoclonal [clone 7H6] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
ALOX15 / 15-Lipoxygenase Antibody - Anti-ALOX15 / 15 Lipoxygenase 1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Mouse Monoclonal [clone 3D8] (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   $495.00
ALOX15 / 15-Lipoxygenase Antibody - Anti-ALOX15 / 15 Lipoxygenase 1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.
Select
Goat Polyclonal to Human ALOX15 / 15-Lipoxygenase
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
ALOX15 / 15-Lipoxygenase Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-ALOX15 mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI2G3] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Human
Flo, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
ALOX15 / 15-Lipoxygenase Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-ALOX15 mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI2G3] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
ALOX15 / 15-Lipoxygenase Antibody - ALOX15 / 15 Lipoxygenase 1 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human ALOX15 / 15-Lipoxygenase
Rabbit, Mouse, Rat, Pig, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $385.00
ALOX15 / 15-Lipoxygenase Antibody - ALOX15 antibody IHC-paraffin: Mouse Lung Tissue.
Select
Rabbit Polyclonal to Human ALOX15 / 15-Lipoxygenase
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg   0.5mg/ml   $355.00
ALOX15 / 15-Lipoxygenase Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using ALOX15 Polyclonal Antibody at dilution of 1:60.
Select
Rabbit Polyclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl   0.6mg/ml   $205.00; 60µl   0.6mg/ml   $235.00; 120µl   0.6mg/ml   $295.00; 200µl   0.6mg/ml   $395.00
ALOX15 / 15-Lipoxygenase Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Mouse Monoclonal [clone 7H6] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
ALOX15 / 15-Lipoxygenase Antibody - IHC of paraffin-embedded Human breast tissue using anti-ALOX15 mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI3G8] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
ALOX15 / 15-Lipoxygenase Antibody - IHC of paraffin-embedded Human breast tissue using anti-ALOX15 mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI3G8] (IgG2b) to Human ALOX15 / 15-Lipoxygenase
Dog, Rat, Human, Monkey
IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
ALOX15 / 15-Lipoxygenase Antibody - Formalin-fixed and paraffin-embedded human lymph tissue reacted with ALOX15 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
Rabbit Polyclonal to Human ALOX15 / 15-Lipoxygenase
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
200µl   $325.00
ALOX15 / 15-Lipoxygenase Antibody - Western blot of recombinant 15-LOX / ALOX15.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Human
WB
FITC Conjugated
200µl   0.5mg/ml   $365.00; 500µl   0.5mg/ml   $560.00; 1ml   0.5mg/ml   $710.00
Select
Rabbit Polyclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $405.00
Select
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
HRP Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
Biotin Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
FITC Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
AP Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
APC Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human ALOX15 / 15-Lipoxygenase
Human
ELISA, IHC, WB
PE Conjugated
100µl   $710.00
ALOX15 / 15-Lipoxygenase Antibody - Immunohistochemistry of paraffin-embedded rat lung tissue.
Select
Rabbit Polyclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Mouse, Rat, Human
IHC, WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $315.00; 200µl   $425.00
ALOX15 / 15-Lipoxygenase Antibody
Select
Rabbit Polyclonal to Human ALOX15 / 15-Lipoxygenase
Human
IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $275.00
ALOX15 / 15-Lipoxygenase Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALOX15 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALOX15.
Select
Mouse Monoclonal [clone OTI8C5] (IgG2a) to Human ALOX15 / 15-Lipoxygenase
Human
IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Rabbit Polyclonal to Human ALOX15 / 15-Lipoxygenase
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human ALOX15 / 15-Lipoxygenase
Mouse, Rat, Human, Monkey
IHC, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Viewing 1-25 of 53 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).