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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ALOX12 / 12 Lipoxygenase

arachidonate 12-lipoxygenase

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.

Gene Name: arachidonate 12-lipoxygenase
Synonyms: ALOX12, 12S-lipoxygenase, 12-lipoxygenase, 12S-LOX, 12(S)-lipoxygenase, 12-LOX, 12 Lipoxygenase, Arachidonate 12-lipoxygenase, LOG12, Platelet 12-LOX, Platelet-type 12-lipoxygenase, Platelet-type lipoxygenase 12
Target Sequences: NM_000697 NP_000688.2 P18054

Filtered by: None
Type
Custom (2)
Sandwich (5)
Sandwich CLIA (1)
Target
ALOX12 / 12 Lipoxygenase (8)
Reactivity
Human (7)
Mouse (1)
Sample Type
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (5)
Serum (5)
Tissue Homogenates (3)
Showing 1-8 of 8 results

Human ALOX12 / 12 Lipoxygenase ELISA Kit (Sandwich ELISA) - LS-F9553
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1plate  $740.00
LSBio image for ELISA Kit

Human ALOX12 / 12 Lipoxygenase ELISA Kit (Sandwich ELISA) - LS-F22205
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Mouse ALOX12 / 12 Lipoxygenase ELISA Kit (Custom ELISA) - LS-F18911
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Human ALOX12 / 12 Lipoxygenase ELISA Kit (Custom ELISA) - LS-F18912
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Human ALOX12 / 12 Lipoxygenase ELISA Kit (CLIA) - LS-F30387
Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Human ALOX12 / 12 Lipoxygenase ELISA Kit (Sandwich ELISA) - LS-F36590
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $790.00
LSBio image for ELISA Kit

Human ALOX12 / 12 Lipoxygenase ELISA Kit (Sandwich ELISA) - LS-F27054
Sandwich
96-Well Strip Plate
Human
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Human ALOX12 / 12 Lipoxygenase ELISA Kit (Sandwich ELISA) - LS-F51449
Sandwich
96-Well Strip Plate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1plate  $975.00
LSBio image for ELISA Kit
Showing 1-8 of 8 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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