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ALG2

ALG2, alpha-1,3/1,6-mannosyltransferase

ALG2 is a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.

Gene Name:	ALG2, alpha-1,3/1,6-mannosyltransferase
Synonyms:	ALG2, CDGIi, HALPG2, Homolog of yeast ALG2, NET38
Target Sequences:	NM_033087 NP_149078.1 Q9H553

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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