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ALDH7A1

aldehyde dehydrogenase 7 family, member A1

ALDH7A1 is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.

Gene Name: aldehyde dehydrogenase 7 family, member A1
Synonyms: ALDH7A1, 26g turgor protein homolog, EPD, PDE, Alpha-AASA dehydrogenase, Antiquitin-1, ATQ1, Betaine aldehyde dehydrogenase, p6c dehydrogenase
Target Sequences: NM_001182 NP_001173.2 P49419

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Products
Proteins (9)
Over-Expression Lysate (3)
Recombinant (6)
ALDH7A1 (9)
No (9)
GST (1)
His (4)
Myc-DDK (Flag) (4)
Human (6)
Mouse (1)
Rat (1)
293T Cells (2)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
ALDH7A1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
58.3 kDa
100 µg/$494
ALDH7A1 Protein - 12.5% SDS-PAGE of human ALDH7A1 stained with Coomassie Blue
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Wheat Germ Extract
GST
81.8 kDa
10 µg/$479; 25 µg/$670
ALDH7A1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
55.2 kDa
20 µg/$150
ALDH7A1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
58.3 kDa
20 µg/$150
Select
E. coli
His
56 kDa
50 µg/$721
ALDH7A1 Protein - Purified recombinant protein ALDH7A1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
55.2 kDa
20 µg/$1,107
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E. coli
His
56.9 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
ALDH7A1 Protein - Recombinant Aldehyde Dehydrogenase 7 Family, Member A1 By SDS-PAGE
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E. coli
His
57.0 kDa
10 µg/$270; 50 µg/$372; 100 µg/$592; 200 µg/$742; 1 mg/$1,786; 500 µg/$1,352; 5 mg/$2,742; 2 mg/$1,966
ALDH7A1 Protein - Recombinant Aldehyde Dehydrogenase 7 Family, Member A1 By SDS-PAGE
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E. coli
His
59.7 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).