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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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AKR7A2 / AFAR

aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)

Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Gene Name: aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
Synonyms: AKR7A2, AFB1-AR 1, AKR7, AFB1 aldehyde reductase 1, AFB1-AR1, AFAR, AFAR1, Aldoketoreductase 7, SSA reductase
Target Sequences: NM_003689 NP_003680.2 O43488

Filtered By: None
Target
AKR7A2 / AFAR (34)
Reactivity
Human (34)
Mouse (5)
Rat (7)
Chimpanzee (3)
Gibbon (3)
Orangutan (3)
Application
IHC (9)
IHC-P (4)
WB (33)
ELISA (10)
ICC (2)
IF (3)
IP (1)
Host
rabbit (26)
mouse (8)
Isotype
IgG (16)
IgG1,k (7)
Clonality
monoclonal mc (7)
polyclonal pc (27)
Format
AP Conjugated (2)
APC Conjugated (2)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (16)
Epitope
N-Terminus (5)
aa82-131 (4)
aa101-129 (1)
aa84-359 (1)
Publications
No (34)
Showing 1-25 of 34 results

AKR7A2 / AFAR Antibody LS-C482275
Rabbit Polyclonal to Human AKR7A2 / AFAR
Mouse, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Immunohistochemical analysis of AKR7A2 staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of AKR7A2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Immunohistochemical analysis of AKR7A2 staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of AKR7A2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.

AKR7A2 / AFAR Antibody LS-C659220
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
ELISA IF IHC WB
Unconjugated
100µg  $405.00

AKR7A2 / AFAR Antibody (aa84-359) LS-C185612
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
ICC IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $335.00
AKR7A2 antibody detects AKR7A2 protein at cytosol on SkHep1 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SkHep2 xenograft. AKR7A2 antibody dilution:1:500.
Immunofluorescence of paraformaldehyde-fixed HeLa using AKR7 antibody at 1:200 dilution.
AKR7A2 antibody detects AKR7A2 protein at cytosol on SkHep1 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SkHep2 xenograft. AKR7A2 antibody dilution:1:500.
Immunofluorescence of paraformaldehyde-fixed HeLa using AKR7 antibody at 1:200 dilution.

AKR7A2 / AFAR Antibody LS-C675370
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100

AKR7A2 / AFAR Antibody LS-C331369
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Mouse, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded mouse heart using AKR7A2 antibodyat dilution of 1:100 (40x lens).
Immunofluorescence analysis of HeLa cells using AKR7A2 antibody. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse heart using AKR7A2 antibodyat dilution of 1:100 (40x lens).
Immunofluorescence analysis of HeLa cells using AKR7A2 antibody. Blue: DAPI for nuclear staining.

AKR7A2 / AFAR Antibody LS-C675367
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
ELISA IHC IHC-P
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100

AKR7A2 / AFAR Antibody LS-C306188
Mouse Monoclonal (IgG1,k) to Human AKR7A2 / AFAR
Human
ELISA WB
Unconjugated
100µg  $560.00

AKR7A2 / AFAR Antibody (HRP) LS-C540807
Mouse Monoclonal (IgG1,k) to Human AKR7A2 / AFAR
Human
ELISA WB
HRP Conjugated
100µl  $710.00

AKR7A2 / AFAR Antibody (Biotin) LS-C520676
Mouse Monoclonal (IgG1,k) to Human AKR7A2 / AFAR
Human
ELISA WB
Biotin Conjugated
100µl  $710.00

AKR7A2 / AFAR Antibody (FITC) LS-C530718
Mouse Monoclonal (IgG1,k) to Human AKR7A2 / AFAR
Human
ELISA WB
FITC Conjugated
100µl  $710.00

AKR7A2 / AFAR Antibody (PE) LS-C648920
Mouse Monoclonal (IgG1,k) to Human AKR7A2 / AFAR
Human
ELISA WB
PE Conjugated
100µl  $710.00

AKR7A2 / AFAR Antibody (AP) LS-C502753
Mouse Monoclonal (IgG1,k) to Human AKR7A2 / AFAR
Human
ELISA WB
AP Conjugated
100µl  $710.00

AKR7A2 / AFAR Antibody (APC) LS-C512461
Mouse Monoclonal (IgG1,k) to Human AKR7A2 / AFAR
Human
ELISA WB
APC Conjugated
100µl  $710.00

AKR7A2 / AFAR Antibody (aa101-129) LS-C99074
Rabbit Polyclonal to Human AKR7A2 / AFAR
Mouse, Human
IHC WB
Unconjugated
400µl  $305.00
Western blot of anti-AKR7A2 antibody in 293 cell line lysates (35 ug/lane). AKR7A2 (arrow) was detected using the purified antibody. Western blot of anti-AKR7A2 Antibody in mouse liver tissue lysates (35 ug/lane). AKR7A2 (arrow) was detected using the purified antibody.
Western blot of anti-AKR7A2 antibody in 293 cell line lysates (35 ug/lane). AKR7A2 (arrow) was detected using the purified antibody. Western blot of anti-AKR7A2 Antibody in mouse liver tissue lysates (35 ug/lane). AKR7A2 (arrow) was detected using the purified antibody.

AKR7A2 / AFAR Antibody LS-C192489
Rabbit Polyclonal to Human AKR7A2 / AFAR
Mouse, Rat, Human
IHC WB
Unconjugated
100µl  $385.00
Western blot of AKR7A2 pAb in extracts from HepG2 cells.
Western blot of AKR7A2 pAb in extracts from HepG2 cells.

AKR7A2 / AFAR Antibody LS-C137240
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Rat, Human
IHC WB
Unconjugated
100µl  $255.00
Immunohistochemistry Image
Western blot Image
Immunohistochemistry Image
Western blot Image

AKR7A2 / AFAR Antibody LS-C309395
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
IP WB
Unconjugated
100µl  $605.00

AKR7A2 / AFAR Antibody LS-C309394
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
WB
Unconjugated
100µg  $605.00

AKR7A2 / AFAR Antibody (HRP) LS-C540809
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
WB
HRP Conjugated
100µl  $755.00

AKR7A2 / AFAR Antibody (Biotin) LS-C520674
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
WB
Biotin Conjugated
100µl  $755.00

AKR7A2 / AFAR Antibody (APC) LS-C512460
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
WB
APC Conjugated
100µl  $755.00

AKR7A2 / AFAR Antibody (PE) LS-C648919
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Human
WB
PE Conjugated
100µl  $755.00

AKR7A2 / AFAR Antibody (N-Terminus) LS-C347631
Rabbit Polyclonal (IgG) to Human AKR7A2 / AFAR
Mouse, Human
WB
Unconjugated
100µl  $405.00

AKR7A2 / AFAR Antibody (aa82-131) LS-C151875
Rabbit Polyclonal to Human AKR7A2 / AFAR
Rat, Human
WB
Unconjugated
50µg  $365.00
AKR7A2 / AFAR antibody Western Blot of Human Liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
AKR7A2 / AFAR antibody Western Blot of Human Liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

AKR7A2 / AFAR Antibody (N-Terminus) LS-C345648
Rabbit Polyclonal to Human AKR7A2 / AFAR
Human
WB
Unconjugated
50µg  $365.00
Western blot of ARK72 Antibody with human Fetal Lung lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of ARK72 Antibody with human Fetal Lung lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 34 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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