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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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AKR1C4 / Chlordecone Reductase

aldo-keto reductase family 1, member C4

Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

Gene Name: aldo-keto reductase family 1, member C4
Synonyms: AKR1C4, 3-alpha-HSD, 3-alpha-HSD1, Chlordecone reductase, CDR, CHDR, DD-4, Dihydrodiol dehydrogenase 4, C11, DD4, HAKRA
Target Sequences: NM_001818 NP_001809.3 P17516

Filtered By: None
Target
AKR1C4 / Chlordecone Reductase (29)
Reactivity
Human (29)
Mouse (4)
Rat (2)
Application
IHC (9)
IHC-P (5)
WB (26)
ELISA (15)
IF (2)
IP (1)
Peptide-ELISA (1)
Host
rabbit (26)
mouse (2)
goat (1)
Isotype
IgG (23)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (28)
Clone
2C11 (1)
Format
AP Conjugated (2)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (17)
Epitope
aa11-39 (8)
aa1-323 (2)
aa1-217 (1)
aa2-14 (1)
Publications
No (29)
Showing 1-25 of 29 results

AKR1C4 / Chlordecone Reductase Antibody (clone 2C11) IHC-plus™ LS-B5390
Mouse Monoclonal [clone 2C11] (IgG1,k) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg 0.5mg/ml  $485.00
Anti-AKR1C4 antibody IHC of human tonsil, squamous epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of monoclonal antibody to AKR1C4 on HepG2 cell. [antibody concentration 15 ug/ml]
Anti-AKR1C4 antibody IHC of human tonsil, squamous epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of monoclonal antibody to AKR1C4 on HepG2 cell. [antibody concentration 15 ug/ml]

AKR1C4 / Chlordecone Reductase Antibody (aa11-39) LS-C329210
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA WB
Unconjugated
200µl  $530.00

AKR1C4 / Chlordecone Reductase Antibody (aa11-39, Biotin) LS-C212651
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA WB
Biotin Conjugated
200µl 0.45mg/ml  $680.00

AKR1C4 / Chlordecone Reductase Antibody (aa11-39, FITC) LS-C212652
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA WB
FITC Conjugated
200µl  $680.00

AKR1C4 / Chlordecone Reductase Antibody (aa11-39, AP) LS-C212649
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA WB
AP Conjugated
200µl  $680.00

AKR1C4 / Chlordecone Reductase Antibody (aa11-39, APC) LS-C212650
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA WB
APC Conjugated
200µl  $680.00

AKR1C4 / Chlordecone Reductase Antibody (aa11-39, Azide-free, HRP) LS-C212653
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

AKR1C4 / Chlordecone Reductase Antibody (aa11-39, PE) LS-C212654
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA WB
PE Conjugated
200µl  $680.00

AKR1C4 / Chlordecone Reductase Antibody (aa2-14) IHC-plus™ LS-B2759
Goat Polyclonal to Human AKR1C4 / Chlordecone Reductase
Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-AKR1C4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Antibody (0.1 ug/ml) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Anti-AKR1C4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Antibody (0.1 ug/ml) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

AKR1C4 / Chlordecone Reductase Antibody (aa1-323) LS-C375178
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Western blot. All lanes: Aldo-keto reductase family 1 member C4 antibody at 7 ug/ml. Lane 1: HeLa whole cell lysate. Lane 2: HepG 2 whole cell lysate. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 37 kDa. Observed band size: 37 kDa.
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Western blot. All lanes: Aldo-keto reductase family 1 member C4 antibody at 7 ug/ml. Lane 1: HeLa whole cell lysate. Lane 2: HepG 2 whole cell lysate. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 37 kDa. Observed band size: 37 kDa.

AKR1C4 / Chlordecone Reductase Antibody LS-C659416
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA IF WB
Unconjugated
100µg  $435.00

AKR1C4 / Chlordecone Reductase Antibody LS-C401755
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Mouse, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human liver cancer using AKR1C4 Polyclonal Antibody at dilution of 1:30.
Western blot analysis of Mouse liver tissue, using AKR1C4 Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry of Human liver cancer using AKR1C4 Polyclonal Antibody at dilution of 1:30.
Western blot analysis of Mouse liver tissue, using AKR1C4 Polyclonal Antibody at dilution of 1:400.

AKR1C4 / Chlordecone Reductase Antibody LS-C405059
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Mouse, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human liver cancer using AKR1C4 Polyclonal Antibody at dilution of 1:25.
Western blot analysis of Mouse liver tissue, using AKR1C4 Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry of Human liver cancer using AKR1C4 Polyclonal Antibody at dilution of 1:25.
Western blot analysis of Mouse liver tissue, using AKR1C4 Polyclonal Antibody at dilution of 1:200.

AKR1C4 / Chlordecone Reductase Antibody (aa1-323) LS-C375176
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
ELISA IHC IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human liver using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human liver using antibody at 1:100 dilution.

AKR1C4 / Chlordecone Reductase Antibody (aa1-217) LS-C185549
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
IHC IHC-P WB
Unconjugated
100µl 0.83mg/ml  $335.00
IHC of paraffin-embedded gastric ca using AKR1C4 antibody at 1:100 dilution.
Sample (30 ug of whole cell lysate). A: Hela. 10% SDS PAGE. HSD3a antibody. AKR1C4 antibody diluted at 1:1000.
IHC of paraffin-embedded gastric ca using AKR1C4 antibody at 1:100 dilution.
Sample (30 ug of whole cell lysate). A: Hela. 10% SDS PAGE. HSD3a antibody. AKR1C4 antibody diluted at 1:1000.

AKR1C4 / Chlordecone Reductase Antibody LS-C412907
Rabbit Polyclonal to Human AKR1C4 / Chlordecone Reductase
Mouse, Rat, Human
IHC WB
Unconjugated
100µl  $385.00

AKR1C4 / Chlordecone Reductase Antibody LS-C349132
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cell lines.
Western blot analysis of extracts of various cell lines.

AKR1C4 / Chlordecone Reductase Antibody LS-C309396
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
IP WB
Unconjugated
100µl  $605.00

AKR1C4 / Chlordecone Reductase Antibody LS-C483411
Rabbit Polyclonal to Human AKR1C4 / Chlordecone Reductase
Human
ELISA
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

AKR1C4 / Chlordecone Reductase Antibody LS-C483412
Rabbit Polyclonal to Human AKR1C4 / Chlordecone Reductase
Human
ELISA
Unconjugated
100µl  $255.00; 200µl  $305.00; 400µl  $355.00

AKR1C4 / Chlordecone Reductase Antibody LS-C309397
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
WB
Unconjugated
100µg  $605.00

AKR1C4 / Chlordecone Reductase Antibody (HRP) LS-C540805
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
WB
HRP Conjugated
100µl  $755.00

AKR1C4 / Chlordecone Reductase Antibody (AP) LS-C502751
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
WB
AP Conjugated
100µl  $755.00

AKR1C4 / Chlordecone Reductase Antibody (aa11-39) LS-C156219
Rabbit Polyclonal to Human AKR1C4 / Chlordecone Reductase
Human
WB
Unconjugated
400µl  $305.00
AKR1C4 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The AKR1C4 antibody detected the AKR1C4 protein (arrow).
AKR1C4 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The AKR1C4 antibody detected the AKR1C4 protein (arrow).

AKR1C4 / Chlordecone Reductase Antibody LS-C306189
Mouse Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
WB
Unconjugated
50µg  $560.00
Showing 1-25 of 29 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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