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AKIP1 / BCA3

A kinase (PRKA) interacting protein 1

Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade.

Gene Name: A kinase (PRKA) interacting protein 1
Synonyms: AKIP1, A-kinase-interacting protein 1, C11orf17, Koyt binding protein 1, Koyt binding protein 2, PKA-interacting protein, Proline-rich protein BCA3, BCA3, Koyt binding protein 3
Target Sequences: NM_020642 NP_065693.2 Q9NQ31

Publications (1)

1
A-kinase interacting protein 1 regulates the cell proliferation, invasion, migration and angiogenesis of clear cell renal cell carcinoma cells and affects the ERK/c-Myc signaling pathway by binding to Rac1. Yu Zhang, Haijian Zhang, Zhixing Han, Xudong Wang, Xuyu Li, Pengfei Yuan, Shiqi Ji, Qingjun Liu. Experimental and therapeutic medicine. 2022 September;24:558. [Full Text Article] [PubMed:35978938] [PMC:PMC9366277] Related Antibodies: LS-C309384.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).