AIFM1 / AIF / PDCD8

Apoptosis-inducing Factor, Mitochondrion-associated, 1

Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli. AIF is highly conserved between human and mouse and widely expressed.

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Products

Proteins (15)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (5)

Recombinant (9)

Target

AIFM1 / AIF / PDCD8 (15)

Publications

No (15)

Tag

6His, N-terminus (3)

8His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (13)

Source

293T Cells (2)

E. coli (5)

HEK 293 Cells (6)

Wheat Germ Extract (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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AIFM1 / AIF / PDCD8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106275

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.1 kDa

Price:

100 µg/$494

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Human AIFM1 / AIF / PDCD8 Protein (Recombinant GST) (Full Length) - LS-G31489

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

93.3 kDa

Price:

2 µg/$439

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AIFM1 / AIF / PDCD8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116794

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.7 kDa

Price:

100 µg/$710

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Human AIFM1 / AIF / PDCD8 Protein (Recombinant His-SUMO) (aa103-612) - LS-G20467

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

71.5 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human AIFM1 / AIF / PDCD8 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Leu102-Asp613) - LS-G26833

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

57.3 kDa

Price:

200 µl/$283

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Human AIFM1 / AIF / PDCD8 Protein (Over-Expression Lysate 8His, N-terminus) (Leu102-Asp613) - LS-G26688

Source:

HEK 293 Cells

Tag:

8His, N-terminus

Molecular Weight:

57.3 kDa

Price:

100 µg/$298

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Human AIFM1 / AIF / PDCD8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69847

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.7 kDa

Price:

20 µg/$1,107

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Human AIFM1 / AIF / PDCD8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69848

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.1 kDa

Price:

20 µg/$1,107

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Human AIFM1 / AIF / PDCD8 Protein (Recombinant GST, N-terminus) (aa420-529) - LS-G61005

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human AIFM1 / AIF / PDCD8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85674

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.7 kDa

Price:

20 µg/$215

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Human AIFM1 / AIF / PDCD8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85675

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.1 kDa

Price:

20 µg/$150

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Human AIFM1 / AIF / PDCD8 Protein (Recombinant 6His, N-terminus) (Glu121-Asp613) - LS-G140051

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

56.2 kDa

Price:

10 µg/$317; 50 µg/$524

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Human AIFM1 / AIF / PDCD8 Protein (Recombinant His) - LS-G2812

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human AIFM1 / AIF / PDCD8 Protein (Recombinant 6His, N-terminus) (Glu121-Asp613) - LS-G38804

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

56.2kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human AIFM1 / AIF / PDCD8 Protein (Recombinant His-T7) (aa103-322) - LS-G13306

Source:

E. coli

Tag:

His-T7

Molecular Weight:

27.8 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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