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AGPS

alkylglycerone phosphate synthase

Alkylglycerone phosphate synthase (AGPS) belongs to a group of peroxisomal enzymes that catalyze the first step in ether phospholipid biosynthesis which involves the acylation of dihydroxyacetonephosphate followed by the introduction of the ether linkage by alkyl-DHAP synthase. Human AGPS shares a 92% nucleotide and amino acid sequence similarity with the guinea pig sequences, and the human sequence was identified by virtue of this homology. Both proteins contain identical peroxisomal targeting signal 2 sequences in their N-terminal presequences. Deficiency of AGPS in peroxisomes has been found in patients with the following peroxisomal disorders: Zellweger syndrome, rhizomelic chondrodysplasia punctate and adrenoleukodystrophy.

Gene Name: alkylglycerone phosphate synthase
Synonyms: AGPS, ALDHPSY, ADAP-S, ADPS, Alkyl-DHAP synthase, Aging-associated protein 5, ADAS, ADHAPS
Target Sequences: NM_003659 NP_003650.1 O00116

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
AGPS (4)
No (4)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
AGPS Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
72.91 kDa
20 µg/$215
AGPS Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
AGPS Protein - Purified recombinant protein AGPS was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
67 kDa
20 µg/$1,107
AGPS Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
72.91 kDa
100 µg/$710
Viewing 1-4 of 4 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).