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AFF2 / OX19
AF4/FMR2 family, member 2
AFF2 / OX19 is a putative transcriptional activator that is a member of the AF4\FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.
| Gene Name: | AF4/FMR2 family, member 2 |
| Synonyms: | AFF2, AF4/FMR2 family, member 2, AF4/FMR2 family member 2, FMR2, Fragile X mental retardation 2, FRAXE, MRX2, Protein Ox19, FMR2P, OX19, Protein FMR-2 |
| Target Sequences: | NM_002025 NP_002016.2 P51816 |
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