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ADM / Adrenomedullin

adrenomedullin

Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.

Gene Name: adrenomedullin
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: ADM, Adrenomedullin, AM, Preproadrenomedullin
Target Sequences: NM_001124 NP_001115.1 P35318

Publications (2)

1
Suppression of CCL2 angiocrine function by adrenomedullin promotes tumor growth. Akiko Nakayama, Kenneth Anthony Roquid, András Iring, Boris Strilic, Stefan Günther, Min Chen, Lee S Weinstein, Stefan Offermanns. The Journal of experimental medicine. 2023 Janurary;220: [Full Text Article] [PubMed:36374225] [PMC:PMC9665902] Related Antibodies: LS-B15534.
2
Temporal and spatial expression of adrenomedullin and its receptors in the porcine uterus and peri-implantation conceptuses. Sudikshya Paudel, Bangmin Liu, Magdalina J Cummings, Kelsey E Quinn, Fuller W Bazer, Kathleen M Caron, Xiaoqiu Wang. Biology of reproduction. 2021 October;105:876-891. [Full Text Article] [PubMed:34104954] [PMC:PMC8511665]

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ELISA Kits (34)
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ADM / Adrenomedullin (34)
Human (10)
Mouse (6)
Rat (7)
Bovine (1)
Chicken (1)
Dog (3)
Monkey (1)
Pig (2)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (4)
96-Well Strip Plate (29)
No (33)
Yes (1)
Cell Culture Supernatants (5)
Cell Lysates (2)
Cell Supernatant (2)
Plasma (26)
Serum (26)
Tissue Homogenates (12)
ADM / Adrenomedullin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Pig
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$889
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$889
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Microplate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
ADM / Adrenomedullin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Microplate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
ADM / Adrenomedullin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$782
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.781 - 50 pmol/l
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ADM / Adrenomedullin ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
ADM / Adrenomedullin ELISA Kit
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Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
ADM / Adrenomedullin ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$929
ADM / Adrenomedullin ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
ADM / Adrenomedullin ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ADM / Adrenomedullin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ADM / Adrenomedullin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ADM / Adrenomedullin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
25 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ADM / Adrenomedullin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ADM / Adrenomedullin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).