ADK / Adenosine Kinase

adenosine kinase

Adenosine kinase (ATP: adenosine 5-prime-phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. There are 2 ADK transcripts that encode a 345-amino acid form and a 362-amino acid form of the enzyme. These 2 alternately spliced forms differ only at the 5-prime end, where the first four encoded residues of the short form are replaced by 21 residues in the long form. When expressed, both isoforms of the enzyme phosphorylated adenosine with identical kinetics and both required Mg2+ for activity.

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Products

Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

ADK / Adenosine Kinase (9)

Publications

No (9)

Tag

GST (1)

GST, N-terminus (1)

His (2)

His-GST (1)

His-GST-S (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Source

293T Cells (1)

Baculovirus (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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ADK / Adenosine Kinase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118762

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.5 kDa

Price:

100 µg/$494

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Mouse ADK / Adenosine Kinase Protein (Recombinant His-GST-S) (aa1-361) - LS-G24746

Source:

E. coli

Tag:

His-GST-S

Molecular Weight:

70.1 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Human ADK / Adenosine Kinase Protein (Recombinant GST) (Full Length) - LS-G27372

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.58 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ADK / Adenosine Kinase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74322

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.5 kDa

Price:

20 µg/$150

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Human ADK / Adenosine Kinase Protein (Recombinant GST, N-terminus) (aa236-345) - LS-G57712

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ADK / Adenosine Kinase Protein (Recombinant His-GST) (Met1-His345) - LS-G97129

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

68 kDa

Price:

50 µg/$561

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Human ADK / Adenosine Kinase Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64837

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.5 kDa

Price:

20 µg/$1,107

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Human ADK / Adenosine Kinase Protein (Recombinant His) - LS-G780

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261; 20 µg/$298; 100 µg/$454; 500 µg/$1,177

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Human ADK / Adenosine Kinase Protein (Recombinant His) (aa94-339) - LS-G14858

Source:

E. coli

Tag:

His

Molecular Weight:

29.0 kDa

Price:

10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107

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