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Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.
Gene Name: | adiponectin receptor 1 |
Synonyms: | ADIPOR1, Adiponectin receptor 1, Adiponectin Receptor, Adiponectin receptor protein 1, CGI-45, CGI45, ACDCR1, TESBP1A, PAQR1 |
Target Sequences: | NM_015999 NP_057083.2 Q96A54 |
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