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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Adiponectin

adiponectin, C1Q and collagen domain containing

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Gene Name: adiponectin, C1Q and collagen domain containing
Synonyms: ADIPOQ, Adiponectin, ADPN, ACDC, ADIPQTL1, APM-1, APM1, ACRP30, Gelatin-binding protein 28, GBP28, Gelatin-binding protein
Target Sequences: NM_004797 NP_004788.1 Q15848

Publications (1)

1
Expression of adiponectin receptors and effects of adiponectin isoforms in mouse preimplantation embryos. iko, Burku J, Bukovsk A, Fabian D, Rehk P, Koppel J. Human reproduction (Oxford, England). 2010 25:2247-55. (IHC; Mouse) [PubMed:20663797] Related Antibodies: LS-B440.

Filtered by: None
Type
Over-Expression Lysate (4)
Recombinant (60)
Target
Adiponectin (65)
Tag
6His,C-terminus (3)
6His,N-terminus (3)
DDK (5)
DDK,N-terminus (1)
GST,N-terminus (1)
His (11)
His + GST (3)
His + S (1)
His + SUMO (1)
His + T7 (1)
His, N-Terminal (1)
Myc + DDK (5)
Species
Bovine (3)
Chicken (1)
Dog (1)
Human (34)
Mouse (17)
Pig (2)
Rat (5)
Source
293T Cells (2)
CHO Cells (1)
E. coli (38)
HEK 293 Cells (15)
High Five Cells (2)
Human (1)
Human Cells (2)
Sf9 Cells (1)
Wheat Germ Extract (1)
Yeast (1)
Purification
Purified (50)
Low Endotoxin Level
Low endotoxin level (30)
Biologically Active
Biologically active (25)
Animal-free
Animal-free (1)
Publications
No (65)
Showing 1-25 of 65 results

Bovine Adiponectin Protein (Recombinant 6His,N-terminus) (aa18-240) - LS-G23404
Yeast
6His,N-terminus
26.4 kD
1mg  $2,205.00; 500µg  $1,425.00; 200µg  $1,005.00; 50µg 0.8mg/ml  $395.00; 10µg  $325.00; 100µg  $620.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Mouse Adiponectin Protein (Recombinant DDK) - LS-G16903
HEK 293 Cells
DDK
Biologically active
2µg  $195.00; 10µg  $255.00; 1mg  $5,850.00

Human Adiponectin Protein (Recombinant DDK) - LS-G16902
HEK 293 Cells
DDK
Biologically active
2µg  $195.00; 10µg  $255.00; 1mg  $5,850.00

Human Adiponectin Protein (Recombinant His) - LS-G16788
E. coli
His
2µg  $195.00; 10µg  $255.00; 1mg  $4,200.00

Dog Adiponectin Protein (Recombinant His + GST) (aa18-244) - LS-G24065
E. coli
His + GST
54.5 kDa
10µg  $305.00; 50µg  $530.00; 100µg  $725.00; 200µg  $1,050.00; 1mg  $2,700.00; 500µg  $1,200.00
Recombinant Adiponectin By SDS-PAGE

Human Adiponectin Protein (Recombinant) - LS-G37758
None
Biologically active
26.0 kD
25µg  $405.00

Human Adiponectin Protein (Recombinant His) - LS-G5047
HEK 293 Cells
His
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
25.4 kDa. DTT-reduced protein migrates as 28-33 kDa due to glycosylation
10µg  $335.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human Adiponectin Protein (Recombinant His, N-Terminal) (aa108-244) - LS-G135524
E. coli
His, N-Terminal
18.1kDa
5µg  $195.00; 25µg  $255.00; 1mg  $2,940.00

Human Adiponectin Protein (Recombinant GST,N-terminus) (aa111-210) - LS-G61095
Wheat Germ Extract
GST,N-terminus
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE Stained with Coomassie Blue.

Human Adiponectin Protein (Recombinant His) - LS-G2864
E. coli
His
100µg 1mg/ml  $315.00; 0.5mg 1mg/ml  $695.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Mouse Adiponectin Protein (Recombinant) - LS-G27186
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16.5 kDa (SDS-PAGE)
50µg  $295.00; 10µg  $215.00; 1mg  $1,905.00

Adiponectin Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G100394
HEK 293 Cells
Myc + DDK
26.41 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human Adiponectin Protein (Recombinant 6His,N-terminus) (Lys101-Gly219) - LS-G26376
E. coli
6His,N-terminus
14 kDa
10µg  $215.00; 50µg  $275.00; 100µg  $325.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Mouse Adiponectin Protein (Recombinant His) (aa18-247) - LS-G22390
E. coli
His
29 kD
1mg  $1,845.00; 500µg  $1,185.00; 200µg  $710.00; 50µg  $325.00; 10µg  $275.00; 100µg  $445.00

Human Adiponectin Protein (Recombinant) - LS-G23544
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
16.7 kDa
100µg  $445.00; 1mg  $3,030.00; 25µg  $275.00; 500µg  $1,815.00; 5µg  $205.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human Adiponectin Protein (Recombinant) - LS-G27208
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
24.7 kDa (SDS-PAGE)
50µg  $325.00; 10µg  $215.00; 1mg  $2,670.00

Mouse Adiponectin Protein (Recombinant) - LS-G27209
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
24.6 kDa (SDS-PAGE)
50µg  $325.00; 10µg  $215.00; 1mg  $2,670.00

Human Adiponectin Protein (Recombinant) - LS-G27193
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
25~28 kDa (SDS-PAGE)
10µg  $215.00; 1mg  $2,670.00; 50µg  $325.00

Human Adiponectin Protein (Recombinant) - LS-G27154
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16~17 kDa (SDS-PAGE)
50µg  $325.00; 10µg  $215.00; 1mg  $2,670.00

Human Adiponectin Protein (Recombinant) - LS-G27165
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16.6 kDa (SDS-PAGE)
50µg  $295.00; 10µg  $215.00; 1mg  $1,905.00

Mouse Adiponectin Protein (Recombinant His) - LS-G490
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100µg 1mg/ml  $315.00; 0.5mg 1mg/ml  $695.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Mouse Adiponectin Protein (Recombinant) - LS-G493
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100µg 1mg/ml  $275.00; 0.5mg 1mg/ml  $485.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human Adiponectin Protein (Recombinant) - LS-G3605
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100µg 0.5mg/ml  $365.00; 0.5mg 0.5mg/ml  $935.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Rat Adiponectin Protein (Recombinant DDK) (aa16-244) - LS-G3717
HEK 293 Cells
DDK
Biologically active
Less than 0.1 EU/µg protein (determined by LAL method).
~30kDa (SDS-PAGE)
50µg  $395.00
Effect of Adiponectin (rat) (rec.) on the phosphorylation of acetyl-CoA carboxylase (ACC) in C2C12 cells. C2C12 myocytes were treated with 25 ug/ml for 15 minutes after serum starvation for 24 hours. 100 ug per well of total cell lysate was separated on reduced SDS-PAGE gels. Immunoblot analysis was performed to measure phosphorylation of ACC with an anti-phosphoACC antibody. 1: 25 ug/ml of Adiponectin (rat) (rec.). 2: 25 ug/ml of a FLAG-tagged control protein. 3: phosphate-buffered saline.

Adiponectin Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G129492
HEK 293 Cells
Myc + DDK
26.9 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Showing 1-25 of 65 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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