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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
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Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
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Adiponectin

adiponectin, C1Q and collagen domain containing

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Gene Name: adiponectin, C1Q and collagen domain containing
Synonyms: ADIPOQ, Adiponectin, ADPN, ACDC, ADIPQTL1, APM-1, APM1, ACRP30, Gelatin-binding protein 28, GBP28, Gelatin-binding protein
Target Sequences: NM_004797 NP_004788.1 Q15848

Publications (1)

1
Expression of adiponectin receptors and effects of adiponectin isoforms in mouse preimplantation embryos. iko, Burku J, Bukovsk A, Fabian D, Rehk P, Koppel J. Human reproduction (Oxford, England). 2010 25:2247-55. (IHC; Mouse) [PubMed:20663797] Related Antibodies: LS-B440.

Viewing 1-25 of 78 items
Select
HEK 293 Cells
None
2µg   $195.00; 10µg   $255.00; 1mg   $5,850.00
Adiponectin Protein
Select
Yeast
6His,N-terminus
26.4 kD
1mg   $2,205.00; 500µg   $1,425.00; 200µg   $1,005.00; 50µg   0.8mg/ml   $395.00; 10µg   $325.00; 100µg   $620.00
Select
None
Biologically active
26.0 kD
25µg   $405.00
Select
High Five Cells
His
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
35.0 kDa
5µg   $215.00; 25µg   $285.00
Adiponectin Protein
Select
E. coli
His
100µg   1mg/ml   $315.00; 0.5mg   1mg/ml   $695.00
Select
HEK 293 Cells
DDK
2µg   $195.00; 10µg   $255.00; 1mg   $5,850.00
Adiponectin Protein - Recombinant Adiponectin By SDS-PAGE
Select
E. coli
His + GST
54.5 kDa
10µg   $305.00; 50µg   $530.00; 100µg   $725.00; 200µg   $1,050.00; 1mg   $2,700.00
Select
E. coli
His + SUMO
40.4 kD
1mg   $1,845.00; 500µg   $1,185.00; 200µg   $890.00; 50µg   $375.00; 10µg   $305.00; 100µg   $545.00
Select
E. coli
His
29 kD
1mg   $1,845.00; 500µg   $1,185.00; 200µg   $710.00; 50µg   $325.00; 10µg   $275.00; 100µg   $445.00
Adiponectin Protein
Select
HEK 293 Cells
His
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
25.4 kDa. DTT-reduced protein migrates as 28-33 kDa due to glycosylation
10µg   $345.00
Select
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16.5 kDa (SDS-PAGE)
50µg   $295.00; 10µg   $215.00; 1mg   $1,905.00
Select
HEK 293 Cells
DDK
Biologically active
2µg   $195.00; 10µg   $255.00; 1mg   $5,850.00
Select
HEK 293 Cells
DDK
Biologically active
2µg   $195.00; 10µg   $255.00; 1mg   $5,850.00
Select
E. coli
His
2µg   $195.00; 10µg   $255.00; 1mg   $4,200.00
Select
None
26.4 kDa (SDS-PAGE)
300µg   $305.00
Select
None
51.6 kDa
300µg   $305.00
Adiponectin Protein - Purified recombinant protein ADIPOQ was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc + DDK
24.9 kDa
20µg   $890.00
Select
HEK 293 Cells
None
25.7kDa
2µg   $195.00; 10µg   $255.00; 1mg   $5,460.00
Select
E. coli
His, N-Terminal
18.1kDa
5µg   $195.00; 25µg   $255.00; 1mg   $2,940.00
Adiponectin Protein
Select
Sf9 Cells
DDK,C-terminus
24.9 kDa
20µg   $485.00
Adiponectin Protein
Select
Sf9 Cells
DDK,C-terminus
24.7 kDa
20µg   $485.00
Adiponectin Protein
Select
HEK 293 Cells
His, N-Terminal
24.9 kDa
20µg   $890.00
Adiponectin Protein
Select
CHO Cells
DDK,C-terminus
25.7 kDa
50µg   $485.00
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein.
16.6 kDa
25µg   $335.00; 1mg   $3,780.00; 100µg   $710.00
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein.
16.6 kDa
25µg   $335.00; 1mg   $3,780.00; 100µg   $710.00

Viewing 1-25 of 78 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).