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Adiponectin

adiponectin, C1Q and collagen domain containing

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Gene Name: adiponectin, C1Q and collagen domain containing
Synonyms: ADIPOQ, Adiponectin, ADPN, ACDC, ADIPQTL1, APM-1, APM1, ACRP30, Gelatin-binding protein 28, GBP28, Gelatin-binding protein
Target Sequences: NM_004797 NP_004788.1 Q15848

Publications (2)

1
Expression of adiponectin receptors and effects of adiponectin isoforms in mouse preimplantation embryos. iko, Burku J, Bukovsk A, Fabian D, Rehk P, Koppel J. Human reproduction (Oxford, England). 2010 25:2247-55. (IHC; Mouse) [PubMed:20663797] Related Antibodies: LS-B440.
2
5-Hydroxytryptophan Suppresses the Abdominal Fat Deposit and Is Beneficial to the Intestinal Immune Function in Broilers. Hui Wang, Shaoqiong Liu, Jun Li, Liyuan Wang, Xiaojuan Wang, Jingpeng Zhao, Hongchao Jiao, Hai Lin. Frontiers in physiology. 2020 July;11:655. [Full Text Article] [PubMed:32595527] [PMC:PMC7304481] Related Antibodies: LS-C292655.

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Antibodies (254)
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Adiponectin Antibody - Anti-Adiponectin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Adiponectin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
Adiponectin Antibody - The extract of mouse liver was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human adiponectin antibody (1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Arrow indicates the oligomer of mouse adiponectin protein in mouse liver.
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Adiponectin Mouse anti-Human Monoclonal (5H7) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µl/$303; 100 µl/$365
Adiponectin ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Adiponectin ELISA Kit
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Sandwich
96-Well Strip Plate
Canine
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Adiponectin ELISA Kit
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Sandwich
96-Well Strip Plate
Horse
0.156 - 10 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Adiponectin ELISA Kit
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Sandwich
96-Well Microplate
Human
24.69 - 18000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
Adiponectin ELISA Kit
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Sandwich
96-Well Microplate
Hamster
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$822
Adiponectin ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Adiponectin ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$854
Adiponectin ELISA Kit
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Sandwich
96-Well Microplate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum, Urine
1 Plate/$699
Adiponectin ELISA Kit
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Sandwich
96-Well Microplate
Pig
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
Adiponectin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$582
Adiponectin ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
Adiponectin Antibody - Adiponectin antibody. IHC(P): Mouse Lung Tissue.
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Adiponectin Rabbit anti-Rat Polyclonal (aa19-244) Antibody
Mouse, Rat
ELISA, IHC, IHC-Pfa, WB
Unconjugated
10 µg/$318; 100 µg/$470
Adiponectin Antibody - Western blot of recombinant Adiponectin.
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Adiponectin Rabbit anti-Chicken Polyclonal (aa32-244) Antibody
Chicken, Human
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
Adiponectin Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ADIPOQ mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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Adiponectin Mouse anti-Human Monoclonal (aa19-244) (OTI1B2) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
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Adiponectin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rat, Human
IHC, WB
Unconjugated
100 µg/$649
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HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16~17 kDa (SDS-PAGE)
50 µg/$402; 10 µg/$278; 1 mg/$2,653
Adiponectin Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Adiponectin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Adiponectin Antibody - Immunohistochemistry of adiponectin in rat brain tissue with adiponectin antibody at 1 ug/ml.
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Adiponectin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
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Adiponectin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Adiponectin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Adiponectin Mouse anti-Human Monoclonal (HADI 773) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Adiponectin Antibody - Western blot of recombinant Adiponectin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Adiponectin Rabbit anti-Pig Polyclonal (aa17-243) Antibody
Pig, Human
WB
Unconjugated
100 µl/$317; 200 µl/$362; 500 µl/$513; 1 ml/$589; 2 ml/$812; 5 ml/$1,324
Adiponectin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$582
Adiponectin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
Viewing 1-25 of 360 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).