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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADH7 is class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants.
| Gene Name: | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| Synonyms: | ADH7, Alcohol dehydrogenase VII, ADH-4, Alcohol dehydrogenase-7, Gastric alcohol dehydrogenase, Retinol dehydrogenase |
| Target Sequences: | NM_000673 NP_000664.2 P40394 |
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