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ADCY3 / Adenylate Cyclase 3

Adenylate Cyclase 3

ADCY3 / Adenylate Cyclase 3 is adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes.

Gene Name: Adenylate Cyclase 3
Family/Subfamily: Adenylate cyclase , not assigned-Adenylate cyclase
Synonyms: ADCY3, AC-III, AcIII, Adenylyl cyclase 3, AC3, Adenylate cyclase type III, ATP pyrophosphate-lyase 3, Adenylate cyclase 3, Adenylate cyclase type 3, Adenylyl cyclase, type III, KIAA0511
Target Sequences: NM_004036 NP_004027.2 O60266

Publications (2)

1
Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling. Bandarigoda Nipunika Somatilaka, Sun-Hee Hwang, Vivek Reddy Palicharla, Kevin Andrew White, Hemant Badgandi, John Michael Shelton, Saikat Mukhopadhyay. Developmental cell. 2020 September;54:710-726e8. [Full Text Article] [PubMed:32702291] [PMC:PMC9042708] Related Antibodies: LS-C204505.
2
Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E. Skylar I Dewees, Romana Vargová, Katherine R Hardin, Rachel E Turn, Saroja Devi, Joshua Linnert, Uwe Wolfrum, Tamara Caspary, Marek Eliáš, Richard A Kahn. Molecular biology of the cell. 2022 April;33:ar33. [Full Text Article] [PubMed:35196065] [PMC:PMC9250359] Related Antibodies: LS-C204505.

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Products
Antibodies (8)
Primary (8)
ADCY3 / Adenylate Cyclase 3 (8)
Human (8)
Mouse (7)
Rat (7)
IHC (4)
IHC-P (1)
WB (7)
ELISA (4)
ICC (1)
IF (3)
IP (1)
Peptide-ELISA (1)
rabbit (8)
Product Group
IHCPlus (1)
IgG (5)
polyclonal pc (8)
Cy3 Conjugated (1)
Unconjugated (7)
aa1125-1144 (1)
aa855-1144 (1)
No (7)
Yes (1)
ADCY3 / Adenylate Cyclase 3 Antibody - Confocal image of mixed rat neuron-glial cultures stained with our rabbit polyclonal antibody to ACIII (red) and our mouse monoclonal antibody to aII-spectrin (MCA-3D7 green). Note the strong and clean staining of neuronal cilia. Since aII-spectrin is specific for neurons in the CNS, the glial cells in this culture are not recognized by this antibody. The aII-spectrin antibody is also an excellent marker of neuronal plasma membranes.
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ADCY3 / Adenylate Cyclase 3 Rabbit anti-Rat Polyclonal (aa1125-1144) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$417
ADCY3 / Adenylate Cyclase 3 Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using ADCY3 Polyclonal Antibody at dilution of 1:50.
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ADCY3 / Adenylate Cyclase 3 Rabbit anti-Human Polyclonal (aa855-1144) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ADCY3 / Adenylate Cyclase 3 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ADCY3 / Adenylate Cyclase 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC-P, IP, WB
Unconjugated
50 µg/$460
ADCY3 / Adenylate Cyclase 3 Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ADCY3 / Adenylate Cyclase 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ADCY3 / Adenylate Cyclase 3 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using ADCY3 Polyclonal Antibody at dilution of 1:30.
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ADCY3 / Adenylate Cyclase 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ADCY3 / Adenylate Cyclase 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
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ADCY3 / Adenylate Cyclase 3 Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µl/$469
ADCY3 / Adenylate Cyclase 3 Antibody - Western blot analysis of extracts of various cells.
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ADCY3 / Adenylate Cyclase 3 Rabbit anti-Human Polyclonal (Cy3) Antibody
Mouse, Rat, Human
IHC, WB
Cy3 Conjugated
20 µl/$275; 100 µl/$389
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).