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ADAT1 is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described.
Gene Name: | adenosine deaminase, tRNA-specific 1 |
Synonyms: | ADAT1, HADAT1 |
Target Sequences: | NM_012091 NP_036223.2 Q9BUB4 |
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