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ACVRL1

activin A receptor type II-like 1

Activin A receptor, type II-like 1 (also called activin receptor-like kinase 1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The protein (sometimes termed ALK1) shares similar domain structures with 3 other closely related ALK proteins (ALK2, ALK3, and ALK4) that together form a subfamily of receptor serine/threonine kinases. ACVRL1 is most highly expressed in human placenta and lung. ACVRL1 deficiency causes hemorrhagic telangiectasia type 2 (HHT2; MIM 600376) also known as Rendu-Osler-Weber syndrome 2 (ORW2).

Gene Name: activin A receptor type II-like 1
Family/Subfamily: Protein Kinase , Activin/TGFb
Synonyms: ACVRL1, ALK1, Activin receptor-like kinase 1, ALK-1, ACVRLK1, HHT, HHT2, SKR3, TSR-I, ORW2
Target Sequences: NM_000020 NP_000011.2 P37023

☰ Filters
Products
Proteins (14)
Over-Expression Lysate (2)
Recombinant (12)
ACVRL1 (14)
No (14)
ABP-His, N-terminus (1)
Fc, C-terminus (4)
Fc/His,C-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His-Fc (1)
Myc-DDK (Flag) (3)
Human (9)
Mouse (3)
Rat (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (4)
Human Cells (3)
Mammalian Cells (2)
Wheat Germ Extract (2)
Purified (5)
Low endotoxin level (7)
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
37.4 kDa
100 µg/$661; 1 mg/$3,499
ACVRL1 Protein
Select
E. coli
ABP-His, N-terminus
25.9 kDa
50 µg/$419
ACVRL1 Protein - 12.5% SDS-PAGE of human ACVRL1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
78.76 kDa
10 µg/$479; 25 µg/$670
ACVRL1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ACVRL1 Protein - Purified recombinant protein ACVRL1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
55.9 kDa
20 µg/$1,107
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
12.3 kDa
100 µg/$661; 1 mg/$3,499
Select
HEK 293 Cells
Fc/His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39 kDa
200 µg/$1,148
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.1kD
10 µg/$233; 50 µg/$277; 500 µg/$725; 1 mg/$1,113
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.1 kDa
10 µg/$233; 50 µg/$277
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
37.6 kDa
10 µg/$233; 50 µg/$277
Select
Human Cells
His-Fc
Less than 1.0 EU/µg protein (determined by LAL method).
38.7 kDa
200 µg/$1,148
ACVRL1 Protein - Recombinant Activin Receptor Like Kinase 1 (ALK1) by SDS-PAGE
Select
E. coli
His, N-Terminal
29.2kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838
ACVRL1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.9 kDa
100 µg/$710
ACVRL1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.9 kDa
20 µg/$215
Viewing 1-14 of 14 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).