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ACTA1 / Skeletal Muscle Actin

Actin, Alpha 1, Skeletal Muscle

Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus. The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Gene Name: Actin, Alpha 1, Skeletal Muscle
Synonyms: ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, ASMA, NEM3
Target Sequences: NM_001100 NP_001091.1 P68133

Publications (2)

1
How Different Stocking Densities Affect Growth and Stress Status of Acipenser baerii Early Stage Larvae. Lucia Aidos, Alessandra Cafiso, Valentina Serra, Mauro Vasconi, Daniela Bertotto, Chiara Bazzocchi, Giuseppe Radaelli, Alessia Di Giancamillo. Animals: an open access journal from MDPI. 2020 July;10: [Full Text Article] [PubMed:32731504] [PMC:PMC7460203] Related Antibodies: LS-B4203.
2
TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway. Nariaki Miyao, Yukiko Hata, Hironori Izumi, Ryo Nagaoka, Yuko Oku, Ichiro Takasaki, Taisuke Ishikawa, Shinya Takarada, Mako Okabe, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Tomoyuki Yoshida, Hideyuki Hasegawa, Naomasa Makita, Naoki Nishida, Hisashi Mori, Fukiko Ichida, Keiichi Hirono. PloS one. 2020 Apr;15:e0227393. [Full Text Article] [PubMed:32236096] [PMC:PMC7112173] Related Antibodies: LS-C413476.

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Antibodies (68)
Primary (68)
ACTA1 / Skeletal Muscle Actin (68)
Human (64)
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rabbit (52)
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No (66)
Yes (2)
ACTA1 / Skeletal Muscle Actin Antibody - Anti-ACTA1 / ASMA antibody IHC of human lung, bronchial smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal Antibody
Fish, Zebrafish, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$440
ACTA1 / Skeletal Muscle Actin Antibody - Anti-ACTA1 / ASMA antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (3B3) Antibody
Rabbit, Goat, Rat, Pig, Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$460
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (aa3-12) (3B3) Antibody
Chicken, Bovine, Rabbit, Mouse, Goat, Guinea pig, Rat, Pig, Horse, Human, Monkey
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$763
ACTA1 / Skeletal Muscle Actin Antibody - Immunohistochemical analysis of Alpha-actin-1 staining in mouse skeletal muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$321
ACTA1 / Skeletal Muscle Actin Antibody - Immunohistochemistry analysis of paraffin-embedded human muscle tissue, using Actin-alpha-1 Antibody. The picture on the right is blocked with the synthesized peptide.
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ACTA1 / Skeletal Muscle Actin Antibody - Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$316; 100 µl/$386
ACTA1 / Skeletal Muscle Actin Antibody - Western blot All lanes: Acta1 antibody at 2µg/ml Lane 1: Mouse brain tissue Lane 2: Mouse lung tissue Lane 3: Rat muscle tissue Lane 4: Zebrafish lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 42 kDa Observed band size: 42, 56 kDa
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ACTA1 / Skeletal Muscle Actin Antibody - Actin antibody IHC-paraffin. IHC(P): Mouse Spleen Tissue.
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa277-308) Antibody
Mouse, Rat, Hamster, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ACTA1 / Skeletal Muscle Actin Antibody - ACTA1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human colon carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ACTA1 / Skeletal Muscle Actin Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (Biotin) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (FITC) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (APC) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (Azide-free) (HRP) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (PE) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
ACTA1 / Skeletal Muscle Actin Antibody - Immunohistochemical analysis of Alpha-actin-1 staining in human muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
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ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (4A6) Antibody
Mouse, Rat, Human
IF, IHC-P, IP, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ACTA1 / Skeletal Muscle Actin Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using ACTA1 Polyclonal Antibody at dilution of 1:65.
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ACTA1 / Skeletal Muscle Actin Antibody - ACTIN antibody IHC-paraffin. IHC(P): Mouse Intestine Tissue.
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ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa359-377) Antibody
Xenopus, Zebrafish, Horse, Mouse, Dog, Rat, Hamster, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).