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ACOX3
acyl-CoA oxidase 3, pristanoyl
Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined.
| Gene Name: | acyl-CoA oxidase 3, pristanoyl |
| Synonyms: | ACOX3, Acyl-CoA oxidase 3, pristanoyl, BRCACOX, BRCOX, Pristanoyl-CoA oxidase, PRCOX |
| Target Sequences: | NM_003501 NP_003492.2 O15254 |
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