Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Reasearch Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

ACE2 / ACE-2

angiotensin I converting enzyme 2

Angiotensin-Converting Enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.

Gene Name: angiotensin I converting enzyme 2
Family/Subfamily: Protease , Metallopeptidase M2
Synonyms: ACE2, ACE-related carboxypeptidase, ACEH, Metalloprotease MPROT15
Target Sequences: NM_021804 NP_068576.1 Q9BYF1

Publications (2)

1
Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms. Adedeji AO, Severson W, Jonsson C, Singh K, Weiss SR, Sarafianos SG. Journal of virology. 2013 87:8017-28. (IHC; Human) [Full Text Article] [PubMed:23678171] [PMC:PMC3700180] Related Antibodies: LS-C122669.
2
Pancreatic angiotensin-converting enzyme 2 improves glycemia in angiotensin II-infused mice. Chhabra KH, Xia H, Pedersen KB, Speth RC, Lazartigues E. American journal of physiology. Endocrinology and metabolism. 2013 Apr;304:E874-84. [Full Text Article] [PubMed:23462816] [PMC:PMC3625779] Related Antibodies: LS-B3197.

Filtered by: None
Target
ACE2 / ACE-2 (123)
Reactivity
Human (103)
Mouse (23)
Rat (16)
Gibbon (3)
Orangutan (3)
Pig (4)
Application
IHC (59)
IHC-P (18)
WB (113)
Flo (11)
ELISA (50)
IF (6)
IP (3)
Peptide-ELISA (1)
Host
rabbit (99)
mouse (22)
goat (2)
Isotype
IgG (69)
IgG1 (8)
IgG1,k (4)
IgG2a (7)
IgM (1)
IgM,k (1)
Clonality
monoclonal mc (22)
polyclonal pc (101)
Clone
1G4 (2)
881CT16.4.4 (2)
AC18F (2)
AC384 (2)
OTI1D2 (2)
OTI1D6 (2)
OTI2G7 (2)
OTI4C5 (2)
OTI4D2 (2)
Format
AP Conjugated (7)
APC (2)
APC Conjugated (8)
Azide-free (3)
Biotin Conjugated (14)
Carrier-free (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (11)
HRP Conjugated (11)
PE Conjugated (9)
Unconjugated (59)
Epitope
aa18-237 (12)
aa140-172 (8)
aa334-409 (8)
aa392-739 (8)
aa59-90 (8)
aa773-805 (8)
aa18-740 (5)
aa684-733 (4)
Internal (3)
N-Terminus (2)
Lys465 (1)
aa169-183 (1)
aa192-208 (1)
aa416-465 (1)
aa788-805 (1)
Publications
No (121)
Yes (2)
Showing 1-25 of 123 results

IHC-plus™ ACE2 / ACE-2 Antibody LS-B3197
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-ACE-2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACE-2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ ACE2 / ACE-2 Antibody LS-B439
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-ACE-2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of ACE2 in Human Kidney cells with ACE2 antibody at 20 ug/ml.

IHC-plus™ ACE2 / ACE-2 Antibody (aa140-172) LS-B6672
Rabbit Polyclonal to Human ACE2 / ACE-2
Human
Flo, IHC, IHC-P, WB
Unconjugated
200µl  $425.00
Anti-ACE-2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACE-2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

ACE2 / ACE-2 Antibody (aa18-740) LS-C122669
Publications (1)
Publications (1)
Goat Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, IHC, IP, WB
Unconjugated
100µg  $785.00

IHC-plus™ ACE2 / ACE-2 Antibody (aa684-733) LS-B5837
Rabbit Polyclonal to Human ACE2 / ACE-2
Pig, Human
IHC, IHC-P, WB
Unconjugated
100µl  $485.00
Anti-ACE-2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACE2 antibody Western blot of Fetal Kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACE2 / ACE-2 Antibody (aa684-733, HRP) LS-C458089
Rabbit Polyclonal to Human ACE2 / ACE-2
Pig, Orangutan, Gibbon, Human
IHC, IHC-P, WB
HRP Conjugated
100µl  $405.00
Anti-ACE-2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACE2 antibody Western blot of Fetal Kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ ACE2 / ACE-2 Antibody LS-B3196
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-ACE-2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACE-2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ ACE2 / ACE-2 Antibody (aa18-237, clone 1G4) LS-B12781
Mouse Monoclonal [clone 1G4] (IgG1) to Human ACE2 / ACE-2
Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ACE2.

ACE2 / ACE-2 Antibody (Internal) LS-C3701
Rabbit Polyclonal (IgG) to Mouse ACE2 / ACE-2
Mouse
ELISA, WB
Unconjugated
100µg  $755.00

ACE2 / ACE-2 Antibody (aa18-740) LS-C34975
Mouse Monoclonal (IgG2a) to Human ACE2 / ACE-2
Human
ELISA, WB
Unconjugated
100µg  $755.00

ACE2 / ACE-2 Antibody (Internal) LS-C413153
Rabbit Polyclonal to Human ACE2 / ACE-2
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $275.00
Western blot analysis of ACE2 expression in HeLa (A); SP20 (B); PC12 (C) whole cell lysates.

ACE2 / ACE-2 Antibody LS-C347
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, IF, IHC, WB
Unconjugated
0.1mg 1mg/ml  $365.00
IHC of human kidney tissue using ACE2 antibody at 2 ug/ml.
Immunofluorescence of ACE2 in Human Kidney cells with ACE2 antibody at 10 ug/ml.

ACE2 / ACE-2 Antibody LS-C677050
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human gastric cancer at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue at dilution of 1:100

ACE2 / ACE-2 Antibody (aa140-172) LS-C326846
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl  $590.00

ACE2 / ACE-2 Antibody (aa140-172, Biotin) LS-C275131
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl  $740.00

ACE2 / ACE-2 Antibody (aa140-172, FITC) LS-C275132
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl  $740.00

ACE2 / ACE-2 Antibody (aa140-172, APC) LS-C275129
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl  $740.00

ACE2 / ACE-2 Antibody (aa140-172, AP) LS-C275130
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl  $740.00

ACE2 / ACE-2 Antibody (aa140-172, Azide-free, HRP) LS-C275133
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

ACE2 / ACE-2 Antibody (aa140-172, PE) LS-C275134
Rabbit Polyclonal (IgG) to Human ACE2 / ACE-2
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl  $740.00

ACE2 / ACE-2 Antibody (aa18-237, clone OTI4D2) LS-C338898
Mouse Monoclonal [clone OTI4D2] (IgG2a) to Human ACE2 / ACE-2
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Human Kidney tissue using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

ACE2 / ACE-2 Antibody (aa18-237, clone OTI4D2, Carrier-free) LS-C790039
Mouse Monoclonal [clone OTI4D2] (IgG2a) to Human ACE2 / ACE-2
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Human Kidney tissue using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

ACE2 / ACE-2 Antibody LS-C483151
Rabbit Polyclonal to Human ACE2 / ACE-2
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

ACE2 / ACE-2 Antibody (aa18-237, clone OTI2G7) LS-C793864
Mouse Monoclonal [clone OTI2G7] (IgG1) to Human ACE2 / ACE-2
Human
IHC, WB
Unconjugated
100µl 1mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)

ACE2 / ACE-2 Antibody (aa773-805) LS-C100347
Rabbit Polyclonal to Human ACE2 / ACE-2
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human testis tissue reacted with ACE2 (SARS Receptor) Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Showing 1-25 of 123 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).