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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Unfortunately, the antibody (ID:12462) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



ACCN1 / ASIC2

acid-sensing (proton-gated) ion channel 2

ACCN1 / ASIC2 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.

Gene Name: acid-sensing (proton-gated) ion channel 2
Family/Subfamily: Ion Channel , Sodium channel - amiloride-sensitive
Synonyms: ASIC2, ACCN1, ASIC2a, Brain sodium channel 1, Degenerin, ACCN, Acid-sensing ion channel 2, Mammalian degenerin homolog, MDEG, MDEG1, MDEG2, HBNaC1, BNaC1, MAMMALIAN DEGENERIN
Target Sequences: NM_183377 NP_899233.1 Q16515

Publications (11)

1
Regulation of acid-sensing ion channel 1a function by tissue kallikrein may be through channel cleavage. Jingjing Su, Yuping Tang, Ling Liu, Houguang Zhou, Qiang Dong. Neuroscience letters. 2011 490:46-51. (WB; Human, Hamster) [Full Text Article] [PubMed:21167908] Related Antibodies: LS-C93915.
2
Immunohistochemical Detection of the Putative Mechanoproteins ASIC2 and TRPV4 in Avian Herbst Sensory Corpuscles. Cabo R, Gálvez A, Laurà R, San José I, Pastor JF, López-Muñiz A, García-Suárez O, Vega JA. Anatomical record (Hoboken, N.J. : 2007). 2013 296:117-22. (IHC-P; Pigeon) [PubMed:23152301] Related Antibodies: LS-C93915.
3
Acid-sensing ion channel 2 (asic 2) and trkb interrelationships within the intervertebral disc. Cuesta A, Viña E, Cabo R, Vázquez G, Cobo R, García-Suárez O, García-Cosamalón J, Vega JA. International journal of clinical and experimental pathology. 2015 8:10305-14. (WB; Human) [PubMed:26617738] [PMC:PMC4637553] Related Antibodies: LS-B156.
4
Acid-sensing ion channels in healthy and degenerated human intervertebral disc. Cuesta A, Del Valle ME, Garc[Character ed]a-Su[Character e1]rez O, Vi[Character f1]a E, Cabo R, V[Character e1]zquez G, Cobo JL, Murcia A, Alvarez-Vega M, Garc[Character ed]a-Cosamal[Character f3]n J, Vega JA. Connective tissue research. 2014 Jun;55:197-204. [Full Text Article] [PubMed:24432912] Related Antibodies: LS-B156.
5
Acid-sensing ion channels (ASICs) in the taste buds of adult zebrafish. Vi[Character f1]a E, Parisi V, Cabo R, Laur[Character e0] R, L[Character f3]pez-Velasco S, L[Character f3]pez-Mu[Character f1]iz A, Garc[Character ed]a-Su[Character e1]rez O, German[Character e0] A, Vega JA. Neuroscience letters. 2013 Mar;536:35-40. [Full Text Article] [PubMed:23328442] Related Antibodies: LS-B156.
6
Acid-sensing ion channels (ASICs) 2 and 4.2 are expressed in the retina of the adult zebrafish. Parisi V, S[Character e1]nchez-Ramos C, Cabo R, Guerrera MC, Quir[Character f3]s LM, German[Character e0] A, Vega JA, Garc[Character ed]a-Su[Character e1]rez O. Cell and tissue research. Jan; [Full Text Article] [PubMed:25585988] Related Antibodies: LS-B156.
7
Acid-sensing ion channel 2 (ASIC2) is selectively localized in the cilia of the non-sensory olfactory epithelium of adult zebrafish. Vi[Character f1]a E, Parisi V, Abbate F, Cabo R, Guerrera MC, Laur[Character e0] R, Quir[Character f3]s LM, P[Character e9]rez-Varela JC, Cobo T, German[Character e0] A, Vega JA, Garc[Character ed]a-Su[Character e1]rez O. Histochemistry and cell biology. 2015 Jan;143:59-68. [Full Text Article] [PubMed:25161120] Related Antibodies: LS-B156.
8
The sensory innervation of the human pharynx: searching for mechanoreceptors. de Carlos F, Cobo J, Mac[Character ed]as E, Feito J, Cobo T, Calavia MG, Garc[Character ed]a-Su[Character e1]rez O, Vega JA. Anatomical record (Hoboken, N.J. : 2007). 2013 Nov;296:1735-46. [Full Text Article] [PubMed:24123994] Related Antibodies: LS-C93915.
9
Acid-sensing ion channel 2 (ASIC2) in the intestine of adult zebrafish. Levanti MB, Guerrera MC, Calavia MG, Ciriaco E, Montalbano G, Cobo J, German[Character e0] A, Vega JA. Neuroscience letters. 2011 Apr;494:24-8. [Full Text Article] [PubMed:21356277] Related Antibodies: LS-C93915.
10
Immunohistochemical localization of acid-sensing ion channel 2 (ASIC2) in cutaneous Meissner and Pacinian corpuscles of Macaca fascicularis. Cabo R, G[Character e1]lvez MA, San Jos[Character e9] I, Laur[Character e0] R, L[Character f3]pez-Mu[Character f1]iz A, Garc[Character ed]a-Su[Character e1]rez O, Cobo T, Insausti R, Vega JA. Neuroscience letters. 2012 May;516:197-201. [Full Text Article] [PubMed:22708125] Related Antibodies: LS-C93915.
11
ASIC2 is present in human mechanosensory neurons of the dorsal root ganglia and in mechanoreceptors of the glabrous skin. Cabo R, Alonso P, Vi[Character f1]a E, V[Character e1]zquez G, Gago A, Feito J, P[Character e9]rez-Molt[Character f3] FJ, Garc[Character ed]a-Su[Character e1]rez O, Vega JA. Histochemistry and cell biology. Mar;143:267-76. [Full Text Article] [PubMed:25224144] Related Antibodies: LS-C93915.
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Filtered By: None
Target
accn1-asic2 (28)
Reactivity
Human (27)
Mouse (8)
Rat (8)
Bat (4)
Bovine (4)
Chicken (4)
Chimpanzee (6)
Gibbon (6)
Hamster (1)
Horse (8)
Monkey (8)
Rabbit (8)
Zebrafish (4)
Application
IHC (16)
IHC-P (6)
WB (23)
Flo (9)
ELISA (10)
IF (1)
IP (1)
Host
rabbit (28)
Isotype
IgG (17)
Clonality
polyclonal pc (28)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (13)
Epitope
aa120-148 (8)
C-Terminus (4)
aa481-530 (4)
N-Terminus (1)
aa15-26 (1)
aa350-400 (1)
aa470-503 (1)
Publications
No (26)
Yes (2)
Showing 1-25 of 28 results

ACCN1 / ASIC2 Antibody (aa481-530) IHC-plus™ LS-B156
(5)
(5)
Rabbit Polyclonal to Human ACCN1 / ASIC2
Rabbit, Horse, Bat, Human, Monkey
IHC IHC-P WB
Unconjugated
50µg  $485.00
Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B156 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B156 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACCN1 / ASIC2 Antibody (aa481-530, HRP) LS-C432177
Rabbit Polyclonal to Human ACCN1 / ASIC2
Rabbit, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B156 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B156 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACCN1 / ASIC2 Antibody (aa481-530, Biotin) LS-C431957
Rabbit Polyclonal to Human ACCN1 / ASIC2
Rabbit, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B156 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B156 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACCN1 / ASIC2 Antibody (aa481-530, FITC) LS-C431958
Rabbit Polyclonal to Human ACCN1 / ASIC2
Rabbit, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $385.00
Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B156 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B156 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACCN1 / ASIC2 Antibody (aa15-26) IHC-plus™ LS-B4761
Rabbit Polyclonal (IgG) to Mouse ACCN1 / ASIC2
Mouse, Human
IHC IHC-P
Unconjugated
50µl 1mg/ml  $495.00
Anti-ACCN1 antibody IHC of human cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4761 concentration 2.5 ug/ml.
Anti-ACCN1 antibody IHC of human cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4761 concentration 2.5 ug/ml.

ACCN1 / ASIC2 Antibody (aa350-400) LS-C93915
(6)
(6)
Rabbit Polyclonal to Mouse ACCN1 / ASIC2
Mouse, Rat, Hamster, Human
IHC WB
Unconjugated
100µl  $325.00

ACCN1 / ASIC2 Antibody (C-Terminus) LS-C110053
Rabbit Polyclonal to Human ACCN1 / ASIC2
Chicken, Zebrafish, Horse, Rabbit, Mouse, Bovine, Rat, Human, Monkey
WB
Unconjugated
50µg  $365.00
ACCN1 antibody LS-C110053 Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACCN1 antibody LS-C110053 Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACCN1 / ASIC2 Antibody (C-Terminus, HRP) LS-C432828
Rabbit Polyclonal to Human ACCN1 / ASIC2
Chicken, Zebrafish, Rabbit, Mouse, Bovine, Horse, Rat, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
ACCN1 antibody LS-C110053 Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACCN1 antibody LS-C110053 Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACCN1 / ASIC2 Antibody (C-Terminus, Biotin) LS-C432825
Rabbit Polyclonal to Human ACCN1 / ASIC2
Chicken, Zebrafish, Rabbit, Mouse, Bovine, Horse, Rat, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
ACCN1 antibody LS-C110053 Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACCN1 antibody LS-C110053 Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACCN1 / ASIC2 Antibody (C-Terminus, FITC) LS-C432826
Rabbit Polyclonal to Human ACCN1 / ASIC2
Chicken, Zebrafish, Rabbit, Mouse, Bovine, Horse, Rat, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
ACCN1 antibody LS-C110053 Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
ACCN1 antibody LS-C110053 Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACCN1 / ASIC2 Antibody (aa120-148) IHC-plus™ LS-B13586
Rabbit Polyclonal to Human ACCN1 / ASIC2
Human
Flo IHC IHC-P WB
Unconjugated
200µl  $425.00
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot of ACCN1 Antibody in NCI-H460 cell line lysates (35 ug/lane). ACCN1 (arrow) was detected using the purified antibody.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot of ACCN1 Antibody in NCI-H460 cell line lysates (35 ug/lane). ACCN1 (arrow) was detected using the purified antibody.

ACCN1 / ASIC2 Antibody LS-C659709
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
ELISA Flo IF IHC IP WB
Unconjugated
100µg  $405.00

ACCN1 / ASIC2 Antibody (aa120-148) LS-C319274
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
ELISA Flo IHC WB
Unconjugated
200µl  $530.00

ACCN1 / ASIC2 Antibody (aa120-148, Biotin) LS-C250650
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
ELISA Flo IHC WB
Biotin Conjugated
200µl  $680.00

ACCN1 / ASIC2 Antibody (aa120-148, FITC) LS-C250651
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
ELISA Flo IHC WB
FITC Conjugated
200µl  $680.00

ACCN1 / ASIC2 Antibody (aa120-148, APC) LS-C250649
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
ELISA Flo IHC WB
APC Conjugated
200µl  $680.00

ACCN1 / ASIC2 Antibody (aa120-148, AP) LS-C250648
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
ELISA Flo IHC WB
AP Conjugated
200µl  $680.00

ACCN1 / ASIC2 Antibody (aa120-148, PE) LS-C250653
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
ELISA Flo IHC WB
PE Conjugated
200µl  $680.00

ACCN1 / ASIC2 Antibody (aa120-148, Azide-free, HRP) LS-C250652
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
ELISA Flo IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

ACCN1 / ASIC2 Antibody (aa470-503) LS-C93912
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Mouse, Rat, Human
IHC WB
Unconjugated
500µg 500µl 1mg/ml  $325.00

ACCN1 / ASIC2 Antibody LS-C659710
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
ELISA WB
Unconjugated
100µg  $405.00

ACCN1 / ASIC2 Antibody (N-Terminus) LS-C34819
Rabbit Polyclonal (IgG) to Rat ACCN1 / ASIC2
Rat
ELISA WB
Unconjugated
100µg  $755.00

ACCN1 / ASIC2 Antibody LS-C669708
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Human
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

ACCN1 / ASIC2 Antibody LS-C497204
Rabbit Polyclonal (IgG) to Human ACCN1 / ASIC2
Mouse, Rat, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cell lines, using ASIC2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Western blot analysis of extracts of various cell lines, using ASIC2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.

ACCN1 / ASIC2 Antibody LS-C662331
Rabbit Polyclonal to Human ACCN1 / ASIC2
Human
WB
Unconjugated
100µg  $325.00
Western blot - Anti-ACCN1 Picoband Antibody
Western blot - Anti-ACCN1 Picoband Antibody
Showing 1-25 of 28 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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