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ABHD5

abhydrolase domain containing 5

ABHD5 belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.

Gene Name: abhydrolase domain containing 5
Synonyms: ABHD5, CDS, CGI-58, IECN2, NCIE2, CGI58
Target Sequences: NM_016006 NP_057090.2 Q8WTS1

Publications (3)

1
Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training. Alsted TJ, Nybo L, Schweiger M, Fledelius C, Jacobsen P, Zimmermann R, Zechner R, Kiens B. American journal of physiology. Endocrinology and metabolism. 2009 296:E445-53. [PubMed:19106247]
2
Skeletal muscle lipase content and activity in obesity and type 2 diabetes. Jocken JW, Moro C, Goossens GH, Hansen D, Mairal A, Hesselink MK, Langin D, van Loon LJ, Blaak EE. The Journal of clinical endocrinology and metabolism. 2010 95:5449-53. [PubMed:20843949]
3
Alternative splicing and developmental and hormonal regulation of porcine comparative gene identification-58 (CGI-58) mRNA. Li X, Suh Y, Kim E, Moeller SJ, Lee K. Journal of animal science. 2012 90:4346-54. [PubMed:22829614]

☰ Filters
Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
ABHD5 (7)
No (7)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (2)
ABHD5 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
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293T Cells
Myc-DDK (Flag)
38.9 kDa
20 µg/$150
ABHD5 Protein - 12.5% SDS-PAGE of human ABHD5 stained with Coomassie Blue
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Wheat Germ Extract
GST
64.13 kDa
10 µg/$479; 25 µg/$670
ABHD5 Protein - Purified recombinant protein ABHD5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
38.9 kDa
20 µg/$1,107
ABHD5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
2 µg/$439
ABHD5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ABHD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
38.9 kDa
100 µg/$494
Viewing 1-7 of 7 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).