ABAT

4-aminobutyrate aminotransferase

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

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Products

Proteins (13)

Type

Over-Expression Lysate (6)

Recombinant (7)

Target

ABAT (13)

Publications

No (13)

Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

GST (1)

His-T7, N-terminus (2)

Myc-DDK (Flag) (9)

Species

Human (9)

Mouse (1)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (6)

Wheat Germ Extract (1)

Purification

Purified (3)

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ABAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124638

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.47 kDa

Price:

100 µg/$494

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Human ABAT Protein (Recombinant His-T7, N-terminus) (Pro249-Lys500) - LS-G133431

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

32.4kDa

Price:

10 µg/$279; 50 µg/$432; 200 µg/$862; 100 µg/$690; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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ABAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111065

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.2 kDa

Price:

100 µg/$494

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Human ABAT Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64744

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.2 kDa

Price:

20 µg/$1,107

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Human ABAT Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64745

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.2 kDa

Price:

20 µg/$1,107

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Human ABAT Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64746

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.2 kDa

Price:

20 µg/$1,107

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Human ABAT Protein (Recombinant GST) (Full Length) - LS-G27314

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

38.5 kDa

Price:

2 µg/$439

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Human ABAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74051

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.47 kDa

Price:

20 µg/$150

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Human ABAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74052

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.47 kDa

Price:

20 µg/$150

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Human ABAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74053

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.2 kDa

Price:

20 µg/$150

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Human ABAT Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (aa29-500) - LS-G56066

Source:

E. coli

Tag:

10His-SUMO, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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ABAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99103

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.47 kDa

Price:

100 µg/$494

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Mouse ABAT Protein (Recombinant His-T7, N-terminus) (Ile236-Lys500) - LS-G133543

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

33.9kDa

Price:

10 µg/$284; 50 µg/$462; 200 µg/$922; 100 µg/$737; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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