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AADAC

arylacetamide deacetylase

Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.

Gene Name: arylacetamide deacetylase
Synonyms: AADAC, CES5A1, DAC, Arylacetamide deacetylase
Target Sequences: NM_001086 NP_001077.2 P22760

Publications (1)

1
Mapping the Cell-Surface N-Glycoproteome of Human Hepatocytes Reveals Markers for Selecting a Homogeneous Population of iPSC-Derived Hepatocytes. Mallanna SK, Cayo MA, Twaroski K, Gundry RL, Duncan SA. Stem cell reports. 2016 7:543-556. (WB; Human) [Full Text Article] [PubMed:27569060] [PMC:PMC5032032] Related Antibodies: LS-C155827.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).