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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136940-20 | 20 µg | $721 |
| LS-G136940-100 | 100 µg | $1,128 |
Rat ITGB4 / Integrin Beta 4 Protein (Recombinant 6His-SUMO, N-terminus) - LS-G136940
Rat ITGB4 / Integrin Beta 4 Protein (Recombinant 6His-SUMO, N-terminus) - LS-G136940
Description:
ITGB4 / Integrin Beta 4 Protein LS-G136940 is a Recombinant Rat ITGB4 / Integrin Beta 4 produced in E. coli 28-713aa with 6His-SUMO, N-terminus tag(s). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
ITGB4 / Integrin Beta 4 Protein LS-G136940 is a Recombinant Rat ITGB4 / Integrin Beta 4 produced in E. coli 28-713aa with 6His-SUMO, N-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
ITGB4 / Integrin Beta 4
Synonyms
ITGB4 | CD104 | Integrin beta-4 | Integrin Beta 4 | gp150 | CD104 antigen | Integrin beta-4 subunit | Integrin, beta 4
Species
Rat
Modifications
Unmodified
Conjugations
Unconjugated
Tag
6His-SUMO, N-terminus
Region
28-713aa
Predicted Molecular Weight
92.2 kDa
AA Sequence
SLTENVEEFWDKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRADSTHLLVFSTESAFHYEADGANVLAGIMNRNDEKCHLDATGAYTQYKTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHKYFPVSSLGVLQEDSSNIVELLEEAFYRIRSNLDIRALDSPRGLRTEVTSDTLQKTETGSFHIKRGEVGTYNVHLRAVEDIDGTHVCQLAKEDQRGNIHLKPSFSDGLRMDASVICDMCACELQKEVQSARCHYRGDFMCGHCVCNEGWSGKTCNCSTGSLSDTQPCLREGEDKPCSGHGECQCGRCVCYGEGRYEGHFCEYDNFQCPRTSGFLCNDRGRCSMGECVCEPGWTGRSCDCPLSNATCIDSNGGICNGLGFCECGRCHCNQRSSLYTDTTCEINYSAIRLGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDELKKAEEVVEYCSFRDEDDDCTYSYTVEGDGSPGPNSTVLVHKKKDCLPAPS
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 85% by SDS-PAGE
Usage Summary
Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Tris, 50% Glycerol
Storage
Store lyophilized at -20°C or -80°C for up to 1 year. Once reconstituted: store undiluted at 4°C for up to 1 week. Aliquot and store undiluted at -20°C or -80°C for up to 6 months. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ITGB4 / Integrin Beta 4
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/7/2024
Date Requested: 5/7/2024
