Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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NAF-1 / CISD2 Protein (Over-Expression Lysate) - LS-G41720
This is GST-tagged recombinant CISD2 protein, expressed in E. coli, and supplied as a protein lysate. It is sufficient for use as a Western Blot standard and comes pre-loaded with Bromophenol blue dye.
Partiallen
gth
E. coli
E. coli
None
Not Tested
Not Tested
Lyophilized from 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.
CISD2 Protein, CDGSH2 Protein, ERIS Protein, Miner1 Protein, MitoNEET related 1 Protein, MitoNEET-related 1 protein Protein, WFS2 Protein, NAF-1 Protein, Wolfram syndrome 2 Protein, CDGSH iron sulfur domain 2 Protein, ZCD2 Protein
Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca2+ stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
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