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Mouse FGF7 / KGF Protein (Recombinant) - LS-G27214

Catalog Size Price
LS-G27214-10 10 µg Unavailable
LS-G27214-50 50 µg Unavailable
LS-G27214-1 1 mg Unavailable

Most Popular FGF7 / KGF Proteins

Human FGF7 / KGF Protein (Recombinant) - LS-G20
E. coli Expression System
163 AA
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human FGF7 / KGF Protein (Recombinant) - LS-G3663
E. coli Expression System
163 AA
None
Purified / Lyophilized / Biologically Active / Animal-Free / Endotoxin Level: Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
Human FGF7 / KGF Protein (Recombinant) - LS-G4220
E. coli Expression System
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.1 ng/µg of protein.
Human FGF7 / KGF Protein (Recombinant) - LS-G4835
Human Human Cells
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 1.0 EU/µg protein.
Functional Assay Image
Human FGF7 / KGF Protein (Recombinant) - LS-G27132
E. coli Expression System
164 AA
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.2 EU/µg protein (determined by LAL method).

100% Guaranteed
LS-G27214
Recombinant Protein
FGF7 / KGF
Mouse
18.7 kDa (SDS-PAGE)
Keratinocyte Growth Factor (KGF) is a highly specific epithelial mitogen produced by fibroblasts and mesenchymal stem cells. KGF belongs to the heparin binding Fibroblast Growth Factor (FGF) family, and is known as FGF-7. However, in contrast to FGF-1, which binds to all known FGF receptors with high affinity, KGF only binds to a splice variant of the FGF receptor, FGFR2-IIIb. FGFR2-IIIb is expressedby most epithelial cells, indicating KGF’s roleas a paracrine mediator. KGF induces the differentiation and proliferation of various epithelial cells such as keratinocytes in the epidermis, hair follicles and sebaceous glands. KGF is also responsible for wound repair of various tissuesincluding lung, bladder, and kidney. Recombinant mouse Keratinocyte Growth Factor (rmKGF) produced in E. coli is a single non-glycosylated polypeptide chain containing 163 amino acids. A fully biologically active molecule, rmKGF has a molecular mass of 18.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
CNDMSPEQTA TSVNCSSPER HTRSYDYMEG GDIRVRRLFC
RTQWYLRIDK RGKVKGTQEM KNSYNIMEIR TVAVGIVAIK
GVESEYYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY
ASAKWTHSGG EMFVALNQKG IPVKGKKTKK EQKTAHFLPM
AIT
E. coli
E. coli
None
Greater than 95% by non-reducing SDS-PAGE and HPLC
ED50 < 2 ng/ml, as determined by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 5.0x 10^5 units/mg.
Less than 0.2 EU/µg protein (determined by LAL method).
Lyophilized from PBS.
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.
For research use only.

About FGF7 / KGF

P21781 NM_002009 NP_002000.1

FGF7 Protein, FGF-7 Protein, Fibroblast growth factor- 7 Protein, Keratinocyte growth factor Protein, Fibroblast growth factor 7 Protein, HBGF-7 Protein, KGF Protein

FGF7 / KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells.

Requested From: 
Date Requested: 5/25/2018

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