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Mouse DLL4 Recombinant (Human IgG1 Fc) Protein LS-G3829

Ordering

Wt. Vol. Conc. Price
10 µg - - $295
50 µg - 0.9 mg/ml $375
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DLL4 Proteins

Mouse DLL4 Recombinant (Human IgG1 Fc) Protein - LS-G3829
Human HEK 293 Cells
Human IgG1 Fc
Unpurified / Lyophilized / Endotoxin Level: Less than 0.1 EU/µg protein (determined by LAL method).
Functional Assay Image
Human DLL4 Recombinant Protein - LS-G4926
Human HEK 293 Cells
None
Unpurified / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Rat DLL4 Recombinant (His + GST) Protein - LS-G15994
E. coli Expression System
His + GST
Unpurified
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
LS-G3829
Recombinant Protein
DLL4
Mouse
~95kDa (SDS-PAGE)
Signal peptide and extracellular domain of mouse DLL4 (aa 1-532) is fused at the C-terminus to the Fc portion of human IgG1.
aa 1-532
HEK 293 Cells
Human
Human IgG1 Fc
Greater than 90% by SDS-PAGE
Inhibits adipogenesis of 3T3L-1 cells.
Less than 0.1 EU/µg protein (determined by LAL method).
PBS.
Store at +4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid repeat freeze-thaw cycles.
For research use only.

About DLL4

Q9NR61 NM_019074 NP_061947.1

DLL4 Protein, Delta-like 4 protein Protein, Delta like 4 Protein, Delta-like 4 (Drosophila) Protein, Delta-like 4 homolog Protein, Drosophila Delta homolog 4 Protein, Notch ligand DLL4 Protein, Delta 4 Protein, Delta ligand 4 Protein, Delta-like protein 4 Protein, Delta4 Protein, Hdelta2 Protein, Notch ligand delta-2 Protein

Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

Functional Assay

Functional Assay
Adipogenesis inhibition of 3T3L1 cells. 3T3L1 cells were maintained in DMEM, supplemented with 10% fetal bovine serum, penicilin-streptomycin. Adipogenesis was initiated by adding 1 uM Dexamethasone, 0.5mM IBMX, 10 ug/m lnsulin (day 0) until day 2. The medium was replaced every 2 days with new medium containing insulin in the presence or absence of 5 ug/ml mDLL4-Fc (Prod. No. AG-40A-0145), hTNFalpha and hCD137-Fc (Fc control). Staining with Oil Red O was typically performed on day 7.
 

Requested From: United States
Date Requested: 12/11/2016

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