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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136652-20 | 20 µg | $395 |
| LS-G136652-100 | 100 µg | $570 |
| LS-G136652-1 | 1 mg | $1,973 |
Influenza A Virus PA / Polymerase Acidic Protein (Recombinant 6His, N-terminus) - LS-G136652
Influenza A Virus PA / Polymerase Acidic Protein (Recombinant 6His, N-terminus) - LS-G136652
Description:
PA / Polymerase Acidic Protein LS-G136652 is a Recombinant Influenza A Virus PA / Polymerase Acidic Protein produced in Yeast 1-209aa with 6His, N-terminus tag(s). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Specifications
Publications
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Popular PA / Polymerase Acidic Protein Proteins
Request SDS/MSDS
Overview
Description:
PA / Polymerase Acidic Protein LS-G136652 is a Recombinant Influenza A Virus PA / Polymerase Acidic Protein produced in Yeast 1-209aa with 6His, N-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
PA / Polymerase Acidic Protein
Synonyms
PA
Species
Influenza A Virus
Modifications
Unmodified
Conjugations
Unconjugated
Tag
6His, N-terminus
Region
1-209aa
Predicted Molecular Weight
26.6 kDa
AA Sequence
MEDFVRQCFNPMIVELAEKAMKEYGEDLKVETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELGDPNALLKHRFEIIEGRDRTMAWTIVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITG
Expression System
Yeast
Source Species
Yeast
Purification
Greater than 90% by SDS-PAGE
Usage Summary
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Lyophilized from Tris, 50% Glycerol
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PA / Polymerase Acidic Protein
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Popular PA / Polymerase Acidic Protein Proteins
Source:
E. coli
Tag:
6His, N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/28/2024
Date Requested: 4/28/2024
