Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
KuP70/P80 Human Recombinant produced in SF9 insect cells is a glycosylated, polypeptide chain having a molecular mass of 70,638 Dalton for the p70 subunit and 83,528 Dalton for the p80 subunit. Ku (P70/P80) is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.
Greater than 90% by SDS-PAGE
16 mM HEPES, pH 8.0, 16 mM NaCl, 20% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
XRCC6 Protein, 5-dRP lyase Ku70 Protein, 70 kDa subunit of Ku antigen Protein, CTCBF Protein, DNA repair protein XRCC6 Protein, D22S671 Protein, D22S731 Protein, G22P1 Protein, Ku autoantigen, 70kDa Protein, Ku autoantigen p70 subunit Protein, Thyroid-lupus autoantigen p70 Protein, TLAA Protein, CTC75 Protein, KU70 Protein, ML8 Protein, Thyroid-lupus autoantigen Protein
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.